Muscular Strengthening for Paretic Knee Flexor and Extensor by Conventional Physiotherapy on Chronic Hemiplegic Stroke Patients

Not Applicable

Completed

• Conditions: Stroke; Hemiplegia
• Interventions: Procedure: Muscular Strengthening for paretic knee flexor and extensor; Other: conventional physiotherapy

• Registration Number: NCT00570570
• Lead Sponsor: University Hospital, Toulouse

Brief Summary

Gait impairment remain one of the main problem for hemiplegic stroke patients. After the 6 first months, stroke patients are classically described with moderate or no improvement. Here, we want to compare the effectiveness of a flexor and extensor paretic knee muscular strengthening program with conventional physiotherapy delivered by the local physiotherapist of the patient, in a very ecological way.

Detailed Description

Gait impairment remain one of the main problem for most of chronic hemiplegic stroke patients. After the 6 first months, stroke patients are classically described with moderate or no improvement for motor skills. However, physiothertapy is very often delivered to try to increase motor performance. Here, we want to compare the effectiveness of a flexor and extensor paretic knee muscular strengthening program with conventional physiotherapy delivered by the local physiotherapist of the patient, in a very ecological way. Patients will be randomly affected to one group with the same amount of physiotherapy (at least 3 times weekly for 6 weeks). Assessment will be done blindly by another physiotherapist, before, after the 6-week treatment and 6 weeks later to evaluate immediate and remaining benefits of each treatment.

Study Timeline

• Study First Submitted: 2007-12-07
• Study First Submitted QC: 2007-12-10
• Study First Posted: 2007-12-11
• Study Start: 2008-05
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Status Verified: 2015-08
• Last Update Submitted: 2015-08-19
• Last Update Posted: 2015-08-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 91

Inclusion Criteria

• Hemipegia due to ischaemic or hemorrhagic stroke more than 6 months ago
• 1st and unique cerebral lesion (Xscan or MRI)
• ability to walk 15 m with or without cane or crutch
• able to understand and give approved consent
• quadriceps at 3/5 (MRC) or stronger

Exclusion Criteria

• Current treatment with botulinum toxin for spasticity of the paretic flexor or extensor of the knee
• Cardiovascular disease contra-indicating effort and strengthening
• Pregnancy
• Evolving pathology
• Rheumatic disease of the knee contraindicating strengthening
• Aphasia with severe comprehension impairment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
group 1	Muscular Strengthening for paretic knee flexor and extensor	Muscular Strengthening for paretic knee flexor and extensor
group 2	conventional physiotherapy	conventional physiotherapy

Primary Outcome Measures

Name	Time	Method
Gait comfortable speed	3 months

Secondary Outcome Measures

Name	Time	Method
gait analysis (gait maximal speed, kymographic and dynamometric analysis, quality of gait parameter) FIM MOS-SF36 Spasticity (Tardieu Scale)	3 months

Trial Locations

Locations (5)

Service de Médecine Physique et de Réadaptation, Hôpital Pellegrin, CHU de Bordeaux,; 🇫🇷 Bordeaux, France

Centre Mutualiste de Rééducation Fonctionnelle, rue Angély Cavlié; 🇫🇷 Albi, France

Service de Médecine Physique et de Réadaptation, Hôpital Jean Rebeyrol, CHU de Limoges,; 🇫🇷 Limoges, France

Service de Médecine Physique et de Réadaptation, Hôpital de Salies du Salat; 🇫🇷 Salies du Salat, France

Service de Médecine Physique et de Réadaptation, Hôpital Rangueil, CHU de Toulouse, TSA 50032; 🇫🇷 Toulouse, France