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Clinical Trials/NCT00764504
NCT00764504
Completed
Phase 3

Encore Reverse Shoulder Prosthesis

Encore Medical, L.P.23 sites in 1 country516 target enrollmentOctober 2002

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Rotator Cuff Arthropathy
Sponsor
Encore Medical, L.P.
Enrollment
516
Locations
23
Primary Endpoint
American Shoulder and Elbow Surgeons Shoulder Score
Status
Completed
Last Updated
15 years ago

Overview

Brief Summary

The objective of this clinical study is to evaluate the safety and efficacy of the Encore Reverse Shoulder Prosthesis (RSP). The clinical results of the RSP will be compared to clinical results published in literature for rotator cuff arthropathy and salvage procedures.

Registry
clinicaltrials.gov
Start Date
October 2002
End Date
August 2008
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Irreparable rotator cuff or failed hemi or total shoulder arthroplasty with irreparable rotator cuff
  • Evidence of upward displacement of the humeral head with respect to the glenoid
  • Loss of glenohumeral joint space
  • Functional deltoid muscle
  • Patient is likely to be available for evaluation for the duration of the study
  • Visual Analog Pain Scale 5 or greater

Exclusion Criteria

  • Non functional deltoid muscle
  • Active sepsis
  • Excessive glenoid bone loss
  • Pregnancy
  • Neurological abnormalities, which could hinder patient's ability or willingness to follow study procedures. For example, any that may restrict physical activities such as Parkinson's, Multiple Sclerosis, or previous stroke, which affects upper extremity.
  • Mental conditions that may interfere with ability to give an informed consent or willingness to fulfill the study requirements (i.e., severe mental retardation such that the patient cannot understand the informed consent process, global dementia, prior strokes that interfere with the patient's cognitive abilities, senile dementia, and Alzheimer's Disease.
  • Prisoners
  • Conditions that place excessive demand on the implant (i.e. Charcot's joints, muscle deficiencies, refusal to modify postoperative physical activities, skeletal immaturity).
  • Known metal allergy (i.e., jewelry).
  • Visual Analog Pain Scale \<5.

Outcomes

Primary Outcomes

American Shoulder and Elbow Surgeons Shoulder Score

Time Frame: 2-year

The patient self-report section of the ASES is a condition specific scale which is intended to measure functional limitations and pain of the shoulder. On a scale of 0 to 100, the use of their shoulder is measured with 0 = no use and 100 = full use. The assessment is done in two sections. One Pain (measured by the Visual Analog Pain Scale) and the second is a list of 10 questions referred to as the Activities of Daily Living. The results are calculated with the following equation: \[(10 - Visual analog scale pain score) x 5\] + \[(5/3) x Cumulative ADL score\]

Average Range of Motion

Time Frame: 2-year

Physician's assessment of a subject's range of motion in degrees.

Subject Satisfaction With Surgery

Time Frame: 2-year

Each subject had a chance to rate their satisfaction with surgery at each study interval.

Have Surgery Again?

Time Frame: 2-year

Subject satisfaction: subject's willingness to have surgery performed again if necessary.

Neer's "Limited Goals"

Time Frame: 2-year

To meet Neer's limited goals, a subject must report: none, slight or moderate pain with unusual activity and exhibit \>90 degrees active forward elevation and exhibit \>20 degrees of active external rotation.

Radiographic Failures

Time Frame: Post-operative, 3-month, 6-month, 1-year, 2-year

Radiographic failure is defined as a shift in the position of the component \>3mm or 3 degrees, a fracture of the cement mantle, a fracture of the component, or a \>2mm radiolucency completely around either prosthesis.

Safety Assessment

Time Frame: 2-year

Number of device related adverse events and device failures at the 2 year time frame.

Study Sites (23)

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