The Accuracy of Qp/Qs Calculated by Noninvasive Methods in Children With Shunt Dependent Pulmonary Circulation

Seoul National University Hospital1 site in 1 country29 target enrollmentMay 23, 2017

ConditionsAnesthesia, General Congenital Heart Disease Blood Gas Monitoring, Transcutaneous Blood Gas Analysis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Anesthesia, General
Sponsor: Seoul National University Hospital
Enrollment: 29
Locations: 1
Primary Endpoint: the difference between Qp/Qs-monitor and Qp/Qs-blood
Status: Terminated
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

In pediatric cardiac patients with shunt dependent pulmonary circulation, Qp/Qs ratio is a important parameter indicating the balance of pulmonaty and systemic circulation.

This study will calculate Qp/Qs using variables measured using non-invasive monitors (cerebral oximeter and pulse oximeter). This value will be compared with Qp/Qs calculated using variables obtained from blood sample.

Detailed Description

Blood sampling will be performed in both arterial and central venous lines.

Registry

clinicaltrials.gov

Start Date

May 23, 2017

End Date

July 21, 2020

Last Updated

5 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Seoul National University Hospital

Responsible Party

Principal Investigator

Jin-Tae Kim

Professor

Seoul National University Hospital

Eligibility Criteria

Inclusion Criteria

•pediatric cardiac patients scheduled to cardiac operation (shunt dependent pulmonary circulation)
•preoperative SpO2\<97%

Exclusion Criteria

•unable to measure pulse oximeter or cerebral oximeter signal
•unable to measure SaO2 or SmvO2
•unstable vital sign

Outcomes

Primary Outcomes

the difference between Qp/Qs-monitor and Qp/Qs-blood

Time Frame: within 1 week after surgery

the difference between Qp/Qs-monitor (measure by pulse oximeter and NIRS) and Qp/Qs-blood (measured by blood gas analysis)

Secondary Outcomes

the difference between SpO2 and SaO2(within 1 week after surgery)
the difference between cerebral oximeter score and and SmvO2(within 1 week after surgery)