Investigation of the Effect of Exercise Training in Patient With Sarcopenic Multiple Sclerosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Uskudar University
- Enrollment
- 30
- Primary Endpoint
- Muscle thickness
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
The aim of this clinical trial is exercise in sarcopenic MS patients to demonstrate the effectiveness of education. The main questions it aims to answer are: -Can exercise training make a change in muscle thickness in sarcopenic MS patients?
--Does exercise training have an effect on balance in sarcopenic MS patients?
- Does exercise training have an effect on the risk of falling in sarcopenic MS patients?
Participants will:
They will continue combined exercise applications 3 days a week for 8 weeks. Evaluations will be made before the application and at the end of the 8 weeks. The data will be analyzed afterwards.
Detailed Description
A significant decrease in physical performance is observed in MS patients. The reasons for this can be changes in muscle contractile structures and symptoms such as sarcopenia. Sarcopenia is a disorder characterized by loss of skeletal muscle mass and decrease in muscle strength and physical performance. Loss of muscle mass seen outside of old age is defined as secondary sarcopenia. In recent years, studies on neurological disorders and their relationship with sarcopenia have increased. Early diagnosis of sarcopenia in neurological patients and implementation of applications aimed at this are important from an early stage. The aim of this study is to examine the effect of exercise training in sarcopenic MS patients. In the study, participants will be applied a combined exercise program 3 days a week for 8 weeks. Parameters such as muscle thickness, balance, and fall risk will be evaluated before and after physiotherapy application including aerobic exercise, balance exercises, and strengthening exercises.
Investigators
tuba kolaylı
Lecturer
Uskudar University
Eligibility Criteria
Inclusion Criteria
- •People diagnosed with MS by a neurologist
- •People with ambulation whose EDSS is 4.5 or below
- •People between the ages of 18-50
- •People who do not exercise regularly and are not included in an exercise program
Exclusion Criteria
- •Having been diagnosed with sarcopenia before MS diagnosis
- •Having had an MS attack within the last 30 days
- •Having any musculoskeletal problems that may affect walking and balance
- •Having a diagnosed psychiatric disease that may affect cognitive status
- •Having a neurological disease other than MS
Outcomes
Primary Outcomes
Muscle thickness
Time Frame: 8 weeks
Ultrasound (US) is an easy-to-use imaging method that provides information about both muscle quality and quantity, with no risk of radiation. Muscle thickness will be assessed with US. Muscle thickness assessed with US has been shown to be consistent with gold standard measurements that assess muscle function and thickness.
Secondary Outcomes
- SARC -F(8 weeks)
- Hand grip strength measurement(8 weeks)
- Bioelectrical impedance analysis(8 weeks)
- Timed Up and Go (TUG)(8 weeks)
- Berg Balance Scale (BBS)(8 weeks)
- Fatigue Severity Scale (FSS)(8 weeks)
- 6 Minute Walk Test(8 weeks)