EUCTR2007-002481-35-GB进行中（未招募）不适用
COMPARISON OF HIGH FLOW VERSUS TITRATED OXYGEN THERAPY IN THE ACUTEMANAGEMENT OF ST ELEVATION MYOCARDIAL INFARCTION - The Oxygen in Myocardial Infarction Study
niversity Hospital of South Manchester NHS Foundation Trust0 个研究点目标入组 150 人开始时间: 2008年2月20日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Subjects are eligible to be included in the study if they meet all of the following criteria:
- •(1)Present with ST-Elevation Myocardial Infarction based on the disease diagnostic criteria (see below)
- •(2)Are at least 18 years of age and competent to provide written informed consent before entering the study. Informed consent must be signed by the study participant.
- •Disease Diagnostic Criteria
- •For the purposes of this study, STEMI will include:
- •A history of chest discomfort or ischaemic symptoms of > 20 minutes duration, < 12 hours prior to randomisation and one of the following present on at least one ECG prior to randomisation
- •ST-segment elevation > 1mm in two or more contiguous limb leads or > 2mm in two or more precordial leads.
- •New or presumably new left bundle branch block (LBBB)
- •ST-segment depression > 1mm in two anterior precordial leads (V1 through V4) with clinical history and evidence suggestive of true posterior infarction.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •4.3 Exclusion Criteria
- •(1)Severe Chronic Obstructive Pulmonary Disease (COPD)
- •(2)Known previous myocardial infarction or CABG; Q waves on ECG in territory other than that of presentation myocardial infarction
- •(3) Previous bleomycin treatment
- •(4)Subjects who are not to be admitted to the coronary care unit.
- •(5)Participants who are immediate family members of investigator site personnel directly affiliated with study, whether biological or legally adopted.
- •(6)Women who are known to be pregnant
- •(7)Mental condition rendering the patient unable to understand the nature, scope and possible consequences of the study
- •(8)Cardiogenic shock (systolic blood pressure less than 90 mm Hg lasting more than 30 mins with evidence of tissue hypoperfusion as defined as cold peripheries (extremities colder than core), oliguria (<30 mL/h), or both) at the time of presentation to the emergency department
- •(9)Severe arterial hypoxaemia (oxygen saturation =85%) at time of presentation
研究者
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