EUCTR2006-006246-34-PL进行中（未招募）不适用
Evaluation of the anti-anginal efficacy and safety of oral administration of ivabradine compared to placebo on top of a background therapy with a calcium antagonist (amlodipine or nifedipine) in patients with stable angina pectoris.A 6-week randomised double-blind parallel-group international multicentre study.
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,240
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Male or female aged >= 18 years,
- •- History of chronic stable angina pectoris,
- •- Normal sinus rythm,
- •- Patients having been treated by amlodipine or nifedipine for at least 4 weeks before selection,
- •- Patients with documented coronary artery disease (CAD).
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 682
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 558
排除标准
- •- Recent acute myocardial infarction, coronary bypass surgery or percutaneous coronary intervention,
- •- Resting angina, unstable angina, Prinzmetal angina or microvascular angina,
- •- Patient with a pacemaker or implanted cardioverter-defibrillator,
- •- Patient who cannot perform exercise tests,
- •- Congestive heart failure stage III or IV NYHA, uncontrolled heart failure,
- •- HR < 60 bpm measured on ECG at rest at selection.
研究者
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