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Clinical Study to Evaluate Efficacy and Safety of Aliskiren (150mg & 300mg) Administered Alone and in Combo With Valsartan (160mg and 320mg) in Patients With High Blood Pressure

Phase 3
Completed
Conditions
Hypertension
Registration Number
NCT00219180
Lead Sponsor
Novartis
Brief Summary

To evaluate the efficacy and safety of aliskiren alone and in combination with valsartan given to patients with essential hypertension

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1797
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change from baseline in diastolic blood pressure after week 8
Secondary Outcome Measures
NameTimeMethod
Change from baseline in systolic blood pressure after week 8
Diastolic blood pressure < 90 mmHg or a reduction of > 10 mmHg after 4 and 8 weeks
Blood pressure control target of < 140/90 mmHg after 4 and 8 weeks
Evaluate 24-hour ambulatory blood pressure monitoring in a subset of patients

Trial Locations

Locations (1)

Novartis Pharmaceuticals

🇺🇸

East Hanover, New Jersey, United States

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