Combined Glossopharyngeal Nerve Block With Topical Anesthesia for Enhanced Recovery in Obstructive Sleep Apnea Patients Undergoing Uvulopalatoplasty
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- The recovery time
研究概览
简要总结
Obstructive sleep apnea is a prevalent condition often treated surgically with palatoplasty, which improves airway patency and reduces apneic events. However, postoperative pain and airway discomfort following palatoplasty can be significant, leading to delayed oral intake, increased opioid consumption, and prolonged recovery. Combining an ultrasound-guided glossopharyngeal nerve block with topical airway anesthesia may provide synergistic analgesia and support a safer recovery profile.
详细描述
Obstructive sleep apnea is a prevalent condition often treated surgically with palatoplasty, which improves airway patency and reduces apneic events. However, postoperative pain and airway discomfort following palatoplasty can be significant, leading to delayed oral intake, increased opioid consumption, and prolonged recovery. Enhanced Recovery After Surgery protocols aim to accelerate functional recovery and reduce perioperative morbidity. Combining an ultrasound-guided glossopharyngeal nerve block with topical airway anesthesia may provide effective analgesia and support a smoother recovery profile.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed diagnosis of moderate to severe obstructive sleep apnea.
- •Patients scheduled for elective palatoplasty under general anesthesia.
- •American Society of Anesthesiologists Physical Status class I and II.
排除标准
- •Patients with chronic opioid use.
- •Advanced hepatic, renal, cardiovascular, and neurologic diseases.
研究组 & 干预措施
Group I
The patient will receive the ultrasound-guided glossopharyngeal nerve block combined with topical airway anesthesia.
干预措施: Glossopharyngeal nerve block (Procedure)
Group c
The patient will receive the standard multimodal analgesia.
干预措施: Standard multimodal analgesia (Other)
结局指标
主要结局
The recovery time
时间窗: 1 hour
The time from from inhalational anesthetic discontinuation to the first response to verbal command.
次要结局
- Additional intraoperative analgesia(4 hours)
- Postoperative pain assessment(The first 24 hours postoperative.)
- Total rescue analgesia(The first 24 hours postoperative.)
- Incidence of complications(4 hours)
- Quality of recovery(The first 24 hours postoperative.)
- Additional intraoperative analgesia(4 hours)
- Postoperative pain assessment(The first 24 hours postoperative.)
- Total rescue analgesia(The first 24 hours postoperative.)
- Incidence of complications(4 hours)
- Quality of recovery(The first 24 hours postoperative.)