RISE - Reduce Sitting Time Among Breast Cancer Survivors

Not Applicable

Completed

• Conditions: Sedentary Behavior; Breast Cancer; Sedentary Time

• Registration Number: NCT05260723
• Lead Sponsor: University of California, San Diego

Brief Summary

This 3-month study will test whether a program to reduce sitting time, for breast cancer survivors experiencing some physical limitations, can improve their physical function and other important aspects of quality of life.

Detailed Description

Many cancer survivors experience long-term physical problems following their cancer treatments and can often seem much older than same age peers who were never treated for cancer. This is known as accelerated aging. One way to improve accelerated aging is to increase moderate to vigorous intensity exercise; however, for many cancer survivors, especially those with physical limitations, increasing exercise levels is not possible. Another potential way to improve accelerated aging may be to decrease the amount of time spent sitting. Long periods of sitting are related to many physical and health problems. Cancer survivors spend more than 9 hours a day sitting and often increase the amount they sit after their cancer treatments. This study could help identify realistic intervention targets for many cancer survivors and be used to guide recommendations for improving physical function and quality of life after cancer.

Study Timeline

• Study First Submitted: 2022-02-09
• Study First Submitted QC: 2022-02-18
• Study First Posted: 2022-03-02
• Study Start: 2022-03-29
• Primary Completion: 2023-04-07
• Status Verified: 2023-05
• Study Completion: 2023-05-07
• Last Update Submitted: 2023-05-11
• Last Update Posted: 2023-05-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 21

Inclusion Criteria

• Breast cancer survivors (stages I-IV) at least 1 year post active treatment (e.g., chemotherapy, radiotherapy)
• Breast cancer was treated with chemotherapy, radiation, immunotherapy, and/or endocrine therapy
• self-report difficulties with physical function
• self-report low levels of moderate to vigorous physical activity
• self-report high levels of sitting time

Exclusion Criteria

• medical condition that interferes with ability to safely stand or stay balanced
• other cancer diagnoses that occurred after their breast cancer diagnosis
• Stage IV breast cancer with brain metastases or less than 12 months life-expectancy
• unable to commit to a 3-month study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Retention rate of enrolled participants	3 months	Percent of participants returning for the 3 month measures

Secondary Outcome Measures

Name	Time	Method
4 meter walk test	3 months	Measure of physical functioning
Timed Up and Go (TUG)	3 months	Measure of physical functioning
30-second Sit-to-Stand Test	3 months	Measure of physical functioning
Patient Reported Measurement Information System - Physical Function	3 months	Measure of Self-Report Physical Function, standardized T-score, higher scores indicated better functioning

Trial Locations

Locations (1)

Moores UCSD Cancer Center; 🇺🇸 La Jolla, California, United States