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临床试验/CTRI/2026/03/105162
CTRI/2026/03/105162尚未招募不适用

Comparative assessment of Subclavian vein versus Inferior Vena Cava diameter and collapsibility index for predicting post induction hypotension in obese patients undergoing elective surgeries under general anaesthesia: a prospective observational study.

Department of Anesthesia, AIIMS Bathinda1 个研究点 分布在 1 个国家目标入组 126 人开始时间: 2026年3月12日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
126
试验地点
1

研究概览

简要总结

After Institutional Ethics Committee approval, written informed consent will be obtained from patients. Demographic data, diagnosis, fasting hours, BMI, and comorbidities will be recorded in a patient proforma.In the preoperative area, ultrasound guided measurements of maximum and minimum diameters of the subclavian vein (SCV) and inferior vena cava (IVC) will be taken three times each in supine patients during spontaneous normal breathing. These will be performed by a qualified anesthesiologist using a portable color Doppler ultrasound machine (Model Edge II, FUJIFILM Sonosite Inc, USA).For SCV, a high frequency linear transducer will be placed perpendicular to the clavicles long axis in the supine position, scanning the lateral third of the clavicle for a short axis view. Patients breathe normally, and minimum (dSCVmin) and maximum (dSCVmax) diameters at end expiration and inspiration will be measured in M mode during the same cycle.For IVC, a curved transducer will be placed subxiphoid with the pointer cephalad, moved right and cranial for a long axis view entering the right atrium. Pulse wave Doppler differentiates IVC from aorta. Minimum (dIVCmin) and maximum (dIVCmax) diameters at end inspiration and expiration will be measured in M mode. Mean values from three readings calculate collapsibility index (CI) as (Maximum diameter minus minimum diameter times 100 divided by maximum diameter).Time from probe placement to measurement and feasibility (ability to visualize and measure) will be noted. Data collected via case record form.In the operating theater, standard ASA monitors (ECG, pulse oximetry, NIBP) record baseline heart rate, NIBP, and SpO2. General anesthesia induction uses midazolam 005 mg/kg IV, fentanyl 2 mcg/kg IV, propofol 2 mg/kg IV, vecuronium 01 mg/kg IV; doses noted. The inducing anesthesiologist is blinded to preoperative findings. Loss of consciousness confirmed by vocal response/jaw thrust/eyelash reflex.Vitals monitored continuously; NIBP every 1 minute for 5 minutes, then every 2 minutes for 20 minutes, then every 5 minutes. Postinduction hypotension defined as MAP below 65 mmHg or over 20 percent drop from baseline. Hypotensive episodes treated with fluids/vasopressors at discretion; number and duration noted.Primary objective: Compare diagnostic accuracies of SCV/IVC diameters and CI for predicting postinduction hypotension in obese patients undergoing elective surgery.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients with a BMI greater than or equal to 25 kg per meter square posted for elective surgical procedures.

排除标准

  • Patient refusal to consent Pregnant females Patients with moderate to severe hepatic, renal or respiratory disease Patients with hypotension with systolic BP less than 90 mm of Hg.

研究者

发起方
Department of Anesthesia, AIIMS Bathinda
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Parul Sharma

All India Institute of Medical Sciences

研究点 (1)

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