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Clinical Trials/NCT02420041
NCT02420041
Completed
Not Applicable

Comparison of the Efficacy of Two Techniques for Sacroiliac Joint Injection: Ultrasound Guidance Versus Fluoroscopic Guidance

United States Naval Medical Center, San Diego1 site in 1 country28 target enrollmentOctober 2012

Overview

Phase
Not Applicable
Intervention
Havel's Inc. EchoStim (facet tip) 21 Gauge 4" needle
Conditions
Sacroiliitis
Sponsor
United States Naval Medical Center, San Diego
Enrollment
28
Locations
1
Primary Endpoint
Change in Pain Score From Baseline to 2 Weeks Post-procedure Using the DoD/VA PRS
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The purpose of this research project is to compare two different techniques for performing an injection of the sacroiliac joint. Although both techniques are safe and accurate, the goal of the study is to determine if one technique is better than the other with respect to improvement in a patient's pain, function, and his or her satisfaction. Additionally, the investigators want to determine if one technique is quicker and more efficient than the other.

Detailed Description

Sacroiliac joint dysfunction is a source of low back pain that causes significant pain and disability. Injection of the sacroiliac joint with a local anesthetic/corticosteroid mixture has shown efficacy in treating this condition, when conservative therapy fails. The use of fluoroscopic guidance and anatomic landmarks are traditional methods for performing this injection; however, ultrasound imaging has recently been utilized for performing this procedure. Although studies exist that describe and validate the ultrasound technique, no studies exist that compare the techniques with respect to short-term and long-term outcomes. In this study, the primary objective is to determine if a difference exists between a fluoroscopic-guided technique and ultrasound-guided technique with respect to pain and function. A secondary objective is to compare the two techniques with respect to procedural characteristics.

Registry
clinicaltrials.gov
Start Date
October 2012
End Date
March 2014
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
United States Naval Medical Center, San Diego
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of SIJ dysfunction by history and physical exam
  • History: Either low back pain or buttock pain
  • Exam: Either tenderness to palpation over the SIJ or a positive provocative maneuver (i.e., Patrick's, Gaenslen's, and/or Yeoman's test)
  • Failed a trial of conservative therapy which may included medications, physical therapy, or both
  • Patient agrees to participate in study

Exclusion Criteria

  • Coagulopathy
  • Renal or Hepatic Failure
  • Current Pregnancy or actively pursuing pregnancy
  • Known allergy to local anesthetic or steroids
  • Infection at site of needle placement or SIJ infection
  • Patient unable to consent himself or herself
  • Patient refusal
  • Prior surgical procedures involving the SIJ
  • Body Mass Index \> 35 kg/m2

Arms & Interventions

Fluoroscopic Guidance

Patients referred to the Naval Medical Center-San Diego Pain Medicine Clinic. Need a history and physical showing objective findings of sacroiliac joint (SIJ) dysfunction. If the patient meets inclusion / exclusion criteria, they will be presented with the study. After accepting and being consented, they will then be scheduled. The day of the appointment they will be randomised to Group A or B. In Group A : Fluoroscopy will be used to Guide Needle Placement to inject Steroid into joint. Then complete the multidimensional pain inventory (MPI) and rate their pain on the NRS from 0-11. After procedure, they will rate their pain from 0-10 in the recovery area and then be discharged to home. They will complete an MPI, Patient Global Impression of Change (PGIC), numerical rating scale (NRS), and adverse events questionnaire 1-2 weeks post-procedure and 3 months post-procedure.

Intervention: Havel's Inc. EchoStim (facet tip) 21 Gauge 4" needle

Fluoroscopic Guidance

Patients referred to the Naval Medical Center-San Diego Pain Medicine Clinic. Need a history and physical showing objective findings of sacroiliac joint (SIJ) dysfunction. If the patient meets inclusion / exclusion criteria, they will be presented with the study. After accepting and being consented, they will then be scheduled. The day of the appointment they will be randomised to Group A or B. In Group A : Fluoroscopy will be used to Guide Needle Placement to inject Steroid into joint. Then complete the multidimensional pain inventory (MPI) and rate their pain on the NRS from 0-11. After procedure, they will rate their pain from 0-10 in the recovery area and then be discharged to home. They will complete an MPI, Patient Global Impression of Change (PGIC), numerical rating scale (NRS), and adverse events questionnaire 1-2 weeks post-procedure and 3 months post-procedure.

Intervention: iohexol

Fluoroscopic Guidance

Patients referred to the Naval Medical Center-San Diego Pain Medicine Clinic. Need a history and physical showing objective findings of sacroiliac joint (SIJ) dysfunction. If the patient meets inclusion / exclusion criteria, they will be presented with the study. After accepting and being consented, they will then be scheduled. The day of the appointment they will be randomised to Group A or B. In Group A : Fluoroscopy will be used to Guide Needle Placement to inject Steroid into joint. Then complete the multidimensional pain inventory (MPI) and rate their pain on the NRS from 0-11. After procedure, they will rate their pain from 0-10 in the recovery area and then be discharged to home. They will complete an MPI, Patient Global Impression of Change (PGIC), numerical rating scale (NRS), and adverse events questionnaire 1-2 weeks post-procedure and 3 months post-procedure.

Intervention: triamcinolone/lidocaine

Ultrasound Guidance

Patients referred to the Naval Medical Center-San Diego Pain Medicine Clinic. Need a history and physical showing objective findings of SIJ dysfunction. If the patient meets inclusion / exclusion criteria, they will be presented with the study. After accepting and being consented, they will then be scheduled. The day of the appointment they will be randomised to Group A or B. In Group B Ultrasound will be used to Guide Needle Placement to inject steroid into joint. Then complete the MPI and rate their pain on the NRS from 0-11. After procedure, they will rate their pain from 0-10 in the recovery area and then be discharged to home. They will complete an MPI, Patient Global Impression of Change (PIGC), NRS, and adverse events questionnaire 1-2 weeks post-procedure and 3 months post-procedure.

Intervention: Ultrasound Guided Sacroiliac Joint Injection

Ultrasound Guidance

Patients referred to the Naval Medical Center-San Diego Pain Medicine Clinic. Need a history and physical showing objective findings of SIJ dysfunction. If the patient meets inclusion / exclusion criteria, they will be presented with the study. After accepting and being consented, they will then be scheduled. The day of the appointment they will be randomised to Group A or B. In Group B Ultrasound will be used to Guide Needle Placement to inject steroid into joint. Then complete the MPI and rate their pain on the NRS from 0-11. After procedure, they will rate their pain from 0-10 in the recovery area and then be discharged to home. They will complete an MPI, Patient Global Impression of Change (PIGC), NRS, and adverse events questionnaire 1-2 weeks post-procedure and 3 months post-procedure.

Intervention: Havel's Inc. EchoStim (facet tip) 21 Gauge 4" needle

Ultrasound Guidance

Patients referred to the Naval Medical Center-San Diego Pain Medicine Clinic. Need a history and physical showing objective findings of SIJ dysfunction. If the patient meets inclusion / exclusion criteria, they will be presented with the study. After accepting and being consented, they will then be scheduled. The day of the appointment they will be randomised to Group A or B. In Group B Ultrasound will be used to Guide Needle Placement to inject steroid into joint. Then complete the MPI and rate their pain on the NRS from 0-11. After procedure, they will rate their pain from 0-10 in the recovery area and then be discharged to home. They will complete an MPI, Patient Global Impression of Change (PIGC), NRS, and adverse events questionnaire 1-2 weeks post-procedure and 3 months post-procedure.

Intervention: SonoSite S-nerve

Ultrasound Guidance

Patients referred to the Naval Medical Center-San Diego Pain Medicine Clinic. Need a history and physical showing objective findings of SIJ dysfunction. If the patient meets inclusion / exclusion criteria, they will be presented with the study. After accepting and being consented, they will then be scheduled. The day of the appointment they will be randomised to Group A or B. In Group B Ultrasound will be used to Guide Needle Placement to inject steroid into joint. Then complete the MPI and rate their pain on the NRS from 0-11. After procedure, they will rate their pain from 0-10 in the recovery area and then be discharged to home. They will complete an MPI, Patient Global Impression of Change (PIGC), NRS, and adverse events questionnaire 1-2 weeks post-procedure and 3 months post-procedure.

Intervention: triamcinolone/lidocaine

Outcomes

Primary Outcomes

Change in Pain Score From Baseline to 2 Weeks Post-procedure Using the DoD/VA PRS

Time Frame: 2 weeks post-procedure minus baseline

Study subjects rate their pain on a scale of 0-10 (0=no pain, 10= the highest level of pain experienced), hence the lower the score the better the outcome.

Change in Pain Score From Baseline to 3 Months Post-procedure Using the DoD/VA PRS

Time Frame: 3 months post-procedure minus baseline

Study subjects rate their pain on a scale of 0-10 (0=no pain, 10= the highest level of pain experienced), hence the lower the score the better the outcome.

Difference in Minutes Between a Sacroiliac Joint Injection Done With Ultrasound vs Fluoroscopy

Time Frame: difference in minutes between a sacroiliac joint injection, an expected average of 9 minutes

during procedure from the time monitors are placed on patient to the time of withdrawal of needle from skin

Change in Pain Score From Baseline to 30 Minutes Pre-procedure Using the Defense and Veterans Pain Rating Scale (DoD/VA PRS) 0-10

Time Frame: 30 minutes pre-procedure minus baseline

Study subjects rate their pain on a scale of 0-10 (0=no pain, 10= the highest level of pain experienced), hence the lower the score the better the outcome.

Secondary Outcomes

  • Satisfaction of Procedure as a Measure of Safety and Tolerability Using a Numerical Scale 1-5(3 months post-procedure)
  • Impression of Change of Condition at 2 Weeks Post-procedure Using the Patient Global Impression of Change (PGIC) Scale(2 weeks post-procedure)
  • Change in Pain Score Since Sacroiliac (SI) Injection at 2 Weeks Post-procedure Using the DoD/VA PRS(during/just before sacroiliac (SI) injection and 2 weeks post-procedure)
  • Impression of Change of Condition at 3 Months Post-procedure Using the PGIC Scale(3 months post-procedure)
  • Change in Pain Score Since SI Injection at 3 Months Post-procedure Using the DoD/VA PRS(during/just before sacroiliac (SI) injection and 3 months post-procedure)

Study Sites (1)

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