comparing silver diamine fluoride and sodium fluoride varnish in stopping the caries

Phase 4

Not yet recruiting

• Conditions: healthy

• Registration Number: CTRI/2025/05/086810
• Lead Sponsor: Dr Tommandru Supriya

Brief Summary

• A randomized control study will be conducted among children aged 6-12 years residing in government hostel Visakhapatnam, suburban district, Andhra   Pradesh. Prior to the study written informed consent would be taken from the parents of the children.

•  children who fulfilled the inclusion criteria will be included in the study.

• A preoperative bitewing radiograph is taken to all the children undergoing the study

•   **In Group 1, steps of 38 percent SDF(kedo 38 percent SDF with KI) application:**

• Before doing the procedure any food debris and plaque if present should be removed from the cavities by wiping with wet gauze, carious lesions should not be removed.

• Decayed teeth are isolated and should be kept dry with cotton rolls and gauze.

• Place one drop of SDF in a plastic dappen dish and should be applied onto the carious tooth surfaces with a micro- applicator for 1 minute ,then apply potassium iodide. Remove any excess by gentle blotting using a cotton pellet.

• The children are instructed to avoid drinking, eating or rinsing in the next 30 minutes after the application.

• The children will be recalled at 3,6 and 9month intervals and evaluated for caries arrest with the help of a post operative bitewing radiograph.

• A dfs index and post operative bitewing radiograph is used to record and assess the prevalence of dental caries in children.

• **In Group 2, steps of 5 percent NaF varnish(voco profluoride varnish) application:**

• Before the procedure Any food debris and plaque if present,should be removed from the tooth surfaces thoroughly by wiping with wet gauze.

• We should Isolate the decayed teeth and keep it dry with cotton rolls and gauze.

• A thin coat of 5 percent NaF(voco proflouride) varnish should be applied using a suitable brush to carious teeth.

• The children will be recalled at 3,6 and 9month intervals and evaluated for caries arrest with the help of a post operative bitewing radiograph.

• A dfs index & post operative bitewing radiograph  is used to record and assess the prevalence of dental caries in children.

The children were instructed not to rinse, drink or eat for 2 hours and are asked to refrain from brushing on the same day

Detailed Description

Not available

Study Timeline

• Study Start: 2025-07-06
• Last Update Posted: 2025-12-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• 1.children aged 6-12 years with parental or guardian acceptance and cooperation.
• Children with active carious lesions in either primary,mixed dentition 3.
• Patient with good general health and free of any systemic diseases.
• Children with no allergic reactions to silver.

Exclusion Criteria

• Children with developmental dental abnormalities such as enamel defects.
• Children with known silver allergy.
• Tooth with physiologic root resorption or close to exfoliation.
• Children with extensive caries involvement, including pulpal involvement, pain, mobility, abscess formation, sinus, or fistula.
• Children with special health care needs.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The comparative evaluation of Silver diamine fluoride and sodium fluoride varnish will give an appropriate material in arresting caries progression.	3 months

Secondary Outcome Measures

Name	Time	Method
Caries Recurrence	tooth discoloration

Trial Locations

Locations (1)

Anil neerukonda institute of dental sciences; 🇮🇳 Visakhapatnam, ANDHRA PRADESH, India

Anil neerukonda institute of dental sciences

🇮🇳Visakhapatnam, ANDHRA PRADESH, India

DrTommandru Supriya

Principal investigator

7981577894

sahanya7t@gmail.com