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临床试验/NCT03516201
NCT03516201已完成不适用

Oral Health in Bariatric Patients

University of Göttingen1 个研究点 分布在 1 个国家目标入组 61 人开始时间: 2018年6月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
61
试验地点
1
主要终点
Oral health of obese adults without bariatric surgery - attachment loss

研究概览

简要总结

As few is known about the oral health of bariatric patients, this study aimed to analyze the prevalence and severity of erosive tooth wear, dental caries and periodontal diseases of obese patients who underwent bariatric surgery in comparison to obese patients without bariatric procedures.

详细描述

The prevalence of overweight and obesity is increasing since the 1980s. Being associated with several risk factors such as hypertension, hyperinsulinemia and hyperlipidemia, obesity presents an immediate and long-term health risk for diabetes mellitus, heart diseases, osteoarthritis and certain forms of cancer. For the control of obesity several therapy options have been developed: Beside conservative treatments including change of diet and lifestyle, bariatric surgery is considered as a promising option for patients with severe obesity (BMI ≥ 40 kg/m2). Allowing impressive weight loss from 40 to 80% and effective reduction of comorbidities, bariatric surgery shows some negative/adverse effects as well, like kidney problems, hyperparathyroidism, anemia and metabolic bone diseases. For oral health, two facts are particularly important to consider: Firstly, chronic regurgitation reaching the oral cavity is an important risk factor for erosive tooth wear which initially appear as smooth silky-shining glazed surfaces. Further progress is often associated with hypersensitivities and aesthetic deficits. Over time, often substantial loss can been observed, provoking hypersensitivities and aesthetic deficits. Secondly, depending on the type of bariatric surgery, pronounced postoperative metabolic and nutritional changes can be observed which also might influence oral health. Aim of this study is to analyze the prevalence and severity of erosive tooth wear, dental caries and periodontal diseases of obese patients who underwent bariatric surgery in comparison to obese patients without bariatric procedures.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years
  • BMI ≥ 25 kg/m2 without or after bariatric surgery

排除标准

  • refusal for participation
  • age <18 years
  • BMI <25 kg/m2

研究组 & 干预措施

obese patients after bariatric surgery

obese adults (≥ 18 years) who underwent bariatric surgery

obese adultes without bariatric surgery

obese adults (≥ 18 years) who did not underwent bariatric surgery at the time of the examination

结局指标

主要结局

Oral health of obese adults without bariatric surgery - attachment loss

时间窗: 10-15 Minutes

probing depths (mm) + recessions (mm)

Oral health of obese adults without bariatric surgery - BOP

时间窗: 2 Minutes

BOP (Bleeding on probing, %) as indicator of inflammation

Oral health of obese adults without bariatric surgery - dental caries

时间窗: 2-5 Minutes

ICDAS (International Caries Detection and Assessment System II, 0-6), presence of restaurations/ crowns (yes/no): calculation of DMFT

Oral health of obese adults without bariatric surgery - erosive tooth wear

时间窗: 1-2 Minutes

BEWE (Basic erosive wear examination, 0-3)

次要结局

  • Oral health of obese adults after bariatric surgery - attachment loss(10-15 Min)
  • Oral health of obese adults after bariatric surgery - BOP(2 Minutes)
  • Oral health of obese adults after bariatric surgery - erosive tooth wear(1-2 Minutes)
  • Oral health of obese adults after bariatric surgery - dental caries(2-5 Minutes)

研究者

发起方
University of Göttingen
申办方类型
Other
责任方
Principal Investigator
主要研究者

Philipp Kanzow, Prof. Dr. med. dent., Dr. rer. medic.

Postdoctoral Research Fellow

University of Göttingen

研究点 (1)

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