EXERT-C: Prospective Study of an EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen
研究概览
简要总结
This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 89 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 20-89 years
- •Women of child-bearing potential must verbally confirm lack of pregnancy prior to enrollment. They should also consent to use adequate contraception during the course of the study.
- •Participants must be determined capable of engaging in resistance training by exercise personnel and/or study PI
- •Participants must complete an assessment by EOC staff and be determined safe to engage in the workout regimen by the study exercise personnel.
- •Individuals not deemed safe to participate in the standard EOC exercise program will be referred to physical therapy or elsewhere
排除标准
- •1. Severe arthritic, joint, cardiovascular, or musculoskeletal condition that would interfere with exercise program
研究组 & 干预措施
General cancer patients
All patients undergoing treatment for cancer on an exercise regimen
干预措施: Dose escalated resistance training (Other)
Head and neck cancer patients
All patients undergoing treatment for head and neck cancer on an exercise regime
干预措施: Dose escalated resistance training (Other)
Colorectal cancer patients
All patients undergoing treatment for colorectal cancer on an exercise regime
干预措施: Dose escalated resistance training (Other)
Pancreatic cancer patients
All patients undergoing treatment for pancreatic cancer on an exercise regime
干预措施: Dose escalated resistance training (Other)
Metastatic breast cancer patients
All patients undergoing treatment for metastatic breast cancer on an exercise regime
干预措施: Dose escalated resistance training (Other)
结局指标
主要结局
Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen
时间窗: 3 months
Measurement on bioimpedance analysis machine (Inbody 970)
Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis
时间窗: 3 months
Measurement on bioimpedance analysis machine (Inbody 970)
Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound
时间窗: 3 months
Measurement via ultrasound and calculation with Jackson-Pollack calculations
次要结局
- Determine changes in Y-balance score for each leg(3 months)
- Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen(3 months)
- Determine changes in strength via load measured in pounds from before to after the nutrition and exercise regimen(3 months)
- Determine changes in EQ-5D responses 1-5 and overall score from before to after the nutrition and exercise regimen(3 months)
研究者
Colin Champ, MD
Radiation Oncologist
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)