EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer
- Conditions
- Cancer
- Interventions
- Other: Dose escalated resistance training
- Registration Number
- NCT06083324
- Lead Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
- Brief Summary
This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
- Age 20-89 years
- Women of child-bearing potential must verbally confirm lack of pregnancy prior to enrollment. They should also consent to use adequate contraception during the course of the study.
- Participants must be determined capable of engaging in resistance training by exercise personnel and/or study PI
- Participants must complete an assessment by EOC staff and be determined safe to engage in the workout regimen by the study exercise personnel.
- Individuals not deemed safe to participate in the standard EOC exercise program will be referred to physical therapy or elsewhere
- Severe arthritic, joint, cardiovascular, or musculoskeletal condition that would interfere with exercise program
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Colorectal cancer patients Dose escalated resistance training All patients undergoing treatment for colorectal cancer on an exercise regime Pancreatic cancer patients Dose escalated resistance training All patients undergoing treatment for pancreatic cancer on an exercise regime Metastatic breast cancer patients Dose escalated resistance training All patients undergoing treatment for metastatic breast cancer on an exercise regime General cancer patients Dose escalated resistance training All patients undergoing treatment for cancer on an exercise regimen Head and neck cancer patients Dose escalated resistance training All patients undergoing treatment for head and neck cancer on an exercise regime
- Primary Outcome Measures
Name Time Method Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen 3 months Measurement on bioimpedance analysis machine (Inbody 970)
Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis 3 months Measurement on bioimpedance analysis machine (Inbody 970)
Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound 3 months Measurement via ultrasound and calculation with Jackson-Pollack calculations
- Secondary Outcome Measures
Name Time Method Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen 3 months Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen
Determine changes in strength via load measured in pounds from before to after the nutrition and exercise regimen 3 months Load is calculated by multiplying sets by repetitions by weight lifted for a specific exercise
Determine changes in Y-balance score for each leg 3 months Y-balance score adds up the distance each leg can move in the front and side directions, divided by the length of the hip. This correlates inversely with fall risk.
Determine changes in EQ-5D responses 1-5 and overall score from before to after the nutrition and exercise regimen 3 months EQ-5D asks 5 questions rates from 1-5 and an overall rating of health
Trial Locations
- Locations (1)
AHN CI Exercise Oncology and Resiliency Center
🇺🇸Pittsburgh, Pennsylvania, United States