KCT0004571进行中（未招募）未知
Phase II trial evaluating the efficacy and safety of physician chosen chemotherapy with hormonal therapy in patients with heavily pretreated advanced ovarian cancer: A multicenter pilot study
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 入组人数
- 58
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 19(Year) 至 o Limit（—）
- 性别
- Female
入选标准
- •- Patients with epithelial ovarian, primary peritoneal, or fallopian tube cancer (EOC): including all histologic types
- •-Confirmation of recurrence using biopsy from primary or metastatic tissue
- •-Palliative treatment setting: [(previous progression free or treatment free interval < 6months and 2 prior chemotherapy regimens) or (=3 prior chemotherapy regimens)]
- •-ECOG Performance status 0-2
- •-Measurable lesion
- •- Estimated life time =6months
- •- Adequate hematologic and end organ function
- •- During clinical trial, women of reproductive age should undergo adequate contraception, and should not perform breast feeding. Moreover, women should have negative pregnancy test performed immediately before clinical trial
排除标准
- •-Patients who were diagnosed with other type of primary cancer within 5 years from diagnosis of epithelial ovarian, primary peritoneal, or fallopian tube cancer (EOC): except cervical intraepithelial neoplasm
- •-Cases that investigator decides as inadequate for study
- •-Patient who has not been recovered from recent surgery
- •-Patient having toxicity more than grade 2 of CTCAE originated from previous chemotherapy
- •-Patient receiving immunotherapy or targeted therapy as anticancer therapy
- •-History of venous thromboembolism
- •-Pregnant women or women having possibility of pregnancy
- •-Hypersensitivity for tamoxifen
- •-Patient receiving combined therapy with Anstrozole
- •-Patient having genetic disorders such as galactose intolerance, lapp lactase deficiency or glucose-galactose malaborption
- •-Hypersensitivity for megestrol acetate
研究者
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