Ultrasound-Guided Injection of Hyaluronic Acid Versus Corticosteroid for Treatment of Trigger Finger: Randomized Controlled Study
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Change in Quinnell trigger finger grading system:
研究概览
简要总结
The aim of the study is to compare the therapeutic effects of hyaluronic acid versus steroid injections in treating trigger fingers using ultrasound guidance
详细描述
A prospective randomized controlled study designed to compare the outcomes of injecting patients with trigger finger with hyaluronic acid versus corticosteroid under ultrasound guidance
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult (>18 years)
- •Patients with a clinical diagnosis of trigger finger grade 1-3 on the Quinnell grading scale and confirmed diagnosis by ultrasound.
排除标准
- •Quinnell's classification grade IV (contracture)
- •Prior injection within 6 months
- •Prior operation of the affected finger
- •Presence of any contracture in the proximal interphalangeal or metacarpophalangeal joint, and
- •History of diabetes, hypothyroidism, and
- •Rheumatic or connective tissue disease
- •Allergy to triamcinolone or hyaluronic acid
- •Pregnancy
- •Secondary triggering e.g. Trauma, infection
- •Trigger finger symptoms duration >6 months
研究组 & 干预措施
Hyaluronic acid
1mL of hyaluronic acid (20 mg/2 mL; Hyalgan, Fidia, Abano Terme, Italy) infiltration at A1-Pulley under ultrasound guidance after subcutaneous 2% lidocaine without epinephrine infiltration of the skin overlying the A1-pulley.
干预措施: hyaluronic acid (20 mg/2 mL) (Drug)
Triamcinolone acetonide
1 mL of Triamcinolone acetonide 10mg/ml infiltration at A1-Pulley under ultrasound guidance after subcutaneous 2% lidocaine without epinephrine infiltration of the skin overlying the A1 pulley.
干预措施: Triamcinolone acetonide 10mg/ml (Drug)
结局指标
主要结局
Change in Quinnell trigger finger grading system:
时间窗: 1 and 3 months post-injection
Change in Quinnell grading overtime within 3 months after injection. Trigger fingers are rated as follows: Grade 0: normal finger movements, Grade 1: uneven finger movements, Grade 2: actively correctable triggering, Grade 3: passively correctable triggering, and Grade 4: locked digit.
次要结局
- Changes in Grip strength(1 and 3 months post-injection)
- The Quick Disability of the Arm, Shoulder and Hand score(1 and 3 months post-injection)
- Visual analogue scale (VAS) of pain(1 and 3 months post-injection)
- Frequency of tender trigger nodules(1 and 3 months post-injection)
- Patient satisfaction with therapy(1 and 3 months post-injection)
- Ultrasound evaluation of A1-Pulley(1 and 3 months post-injection)
研究者
Sahar Said Khalil
Specialist Senior Registrar- Physical Medicine and Rehabilitation Department- Dubai Hospital- UAE( co-affiliation: Assistant Professor Rheumatology, physical Medicine and rehabilitation- Zagazig University- Egypt)
Dubai Health Authority