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Clinical Trials/NCT03552874
NCT03552874
Completed
Not Applicable

The Comparison of Pulmonary and Upper Extremity Functions Between Children With Duchenne Muscular Dystrophy and Healthy Peers

Hacettepe University0 sites47 target enrollmentJanuary 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Duchenne Muscular Dystrophy
Sponsor
Hacettepe University
Enrollment
47
Primary Endpoint
Pulmonary Function Test (PFT)
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Although it is known that the functions of pulmonary and upper limb is affected in late stage of Duchenne Muscular Dystrophy (DMD) negatively, the investigators do not have clear information about its early stage. The aim of this study was to investigate the differences in pulmonary and upper limb functions between children with DMD in early stage and healthy peers.

Registry
clinicaltrials.gov
Start Date
January 1, 2017
End Date
March 31, 2018
Last Updated
7 years ago
Study Type
Observational
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Numan Bulut

Department of Physiotherapy and Rehabilitation, Principal Investigator, Research Assistant

Hacettepe University

Eligibility Criteria

Inclusion Criteria

  • children with DMD was;
  • age between 5-10 years
  • being on treatment with corticosteroids for more than 6 months
  • being at Level I according to Brooke Upper and Lower Extremity Classification Systems
  • Healthy peers;
  • age between 5-10 years
  • not having any diagnosed disease

Exclusion Criteria

  • Children has undergo surgery and disease affect upper extremity or pulmonary function in last six months.

Outcomes

Primary Outcomes

Pulmonary Function Test (PFT)

Time Frame: 5 minutes

The pulmonary function tests of the participants were evaluated with a spirometry. The child was asked to perform the spirometric tests for three times with maximum effort. The child was motivated before each attempt for stronger and longer expiration.The result of Pulmonary function Test were recorded.

The Performance Upper Limb (PUL)

Time Frame: 15 minutes

Upper limb functions of participants were evaluated with The Performance of Upper Limb (PUL) scale. This scale, which was shown to be reliable in DMD, has 22 items in total. It consists of 3 different levels of function: high, mid, and distal. PUL also has four items determining timed performance.

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