The Comparison of Pulmonary and Upper Extremity Functions Between Children With Duchenne Muscular Dystrophy and Healthy Peers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 主要终点
- Pulmonary Function Test (PFT)
研究概览
简要总结
Although it is known that the functions of pulmonary and upper limb is affected in late stage of Duchenne Muscular Dystrophy (DMD) negatively, the investigators do not have clear information about its early stage. The aim of this study was to investigate the differences in pulmonary and upper limb functions between children with DMD in early stage and healthy peers.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 5 Years 至 10 Years（Child）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •children with DMD was;
- •age between 5-10 years
- •being on treatment with corticosteroids for more than 6 months
- •being at Level I according to Brooke Upper and Lower Extremity Classification Systems
- •Healthy peers;
- •age between 5-10 years
- •not having any diagnosed disease
排除标准
- •Children has undergo surgery and disease affect upper extremity or pulmonary function in last six months.
结局指标
主要结局
Pulmonary Function Test (PFT)
时间窗: 5 minutes
The pulmonary function tests of the participants were evaluated with a spirometry. The child was asked to perform the spirometric tests for three times with maximum effort. The child was motivated before each attempt for stronger and longer expiration.The result of Pulmonary function Test were recorded.
The Performance Upper Limb (PUL)
时间窗: 15 minutes
Upper limb functions of participants were evaluated with The Performance of Upper Limb (PUL) scale. This scale, which was shown to be reliable in DMD, has 22 items in total. It consists of 3 different levels of function: high, mid, and distal. PUL also has four items determining timed performance.
次要结局
未报告次要终点
研究者
Numan Bulut
Department of Physiotherapy and Rehabilitation, Principal Investigator, Research Assistant
Hacettepe University