Effects of Antimicrobial Photodynamic Therapy Associated to Biomaterials on Regeneration of Class II Furcation Lesions
Overview
- Phase
- Not Applicable
- Intervention
- Scaling and root planing
- Conditions
- Periodontitis, Chronic
- Sponsor
- University of Sao Paulo
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- Horizontal probing depth
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The aim of this study is to evaluate the additional effect of antimicrobial photodynamic therapy regeneration treatment of mandibular furcation lesions when associated to bovine bone and porcine collagen membrane.
Investigators
Carla Andreotti Damante
Associate professor
University of Sao Paulo
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of class II furcation lesion in mandibular 1st and 2nd molars
- •Mandibular 1st and 2nd molars without caries, erosion or abrasion
Exclusion Criteria
- •Smoking habit
- •Pregnancy
- •Use of antibiotics in the last six months
- •Periodontal treatment in the last six months
- •Endodontic lesion
- •Systemic diseases that impair wound healing
Arms & Interventions
Control
Decontamination of furcation defect with scaling and root planing only.
Intervention: Scaling and root planing
Antimicrobial Photodynamic Therapy
Decontamination of furcation defect with scaling and root planing complemented by antimicrobial photodynamic therapy.
Intervention: Scaling and root planing
Antimicrobial Photodynamic Therapy
Decontamination of furcation defect with scaling and root planing complemented by antimicrobial photodynamic therapy.
Intervention: Toluidine Blue O
Outcomes
Primary Outcomes
Horizontal probing depth
Time Frame: one year
Measured with a periodontal probe (mm). Ideal if 0.
Tomographic Bone filling
Time Frame: One year
Complete filling of furcation defect in tomographic images. Ideal is a radiopaque image similar to neighbor bone.
Secondary Outcomes
- Clinical Attachment Level(one year)
- Probing depth(one year)
- Bleeding on probing(One year)