Effects of Antimicrobial Photodynamic Therapy Associated to Biomaterials on Regeneration of Class II Furcation Lesions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Horizontal probing depth
研究概览
简要总结
The aim of this study is to evaluate the additional effect of antimicrobial photodynamic therapy regeneration treatment of mandibular furcation lesions when associated to bovine bone and porcine collagen membrane.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of class II furcation lesion in mandibular 1st and 2nd molars
- •Mandibular 1st and 2nd molars without caries, erosion or abrasion
排除标准
- •Smoking habit
- •Pregnancy
- •Use of antibiotics in the last six months
- •Periodontal treatment in the last six months
- •Endodontic lesion
- •Systemic diseases that impair wound healing
研究组 & 干预措施
Control
Decontamination of furcation defect with scaling and root planing only.
干预措施: Scaling and root planing (Procedure)
Antimicrobial Photodynamic Therapy
Decontamination of furcation defect with scaling and root planing complemented by antimicrobial photodynamic therapy.
干预措施: Scaling and root planing (Procedure)
Antimicrobial Photodynamic Therapy
Decontamination of furcation defect with scaling and root planing complemented by antimicrobial photodynamic therapy.
干预措施: Toluidine Blue O (Drug)
结局指标
主要结局
Horizontal probing depth
时间窗: one year
Measured with a periodontal probe (mm). Ideal if 0.
Tomographic Bone filling
时间窗: One year
Complete filling of furcation defect in tomographic images. Ideal is a radiopaque image similar to neighbor bone.
次要结局
- Clinical Attachment Level(one year)
- Probing depth(one year)
- Bleeding on probing(One year)
研究者
Carla Andreotti Damante
Associate professor
University of Sao Paulo