Pain after root canal treatment

Phase 4

Not yet recruiting

Conditions: Pulpitis,

Registration Number: CTRI/2021/04/032667

Lead Sponsor: Manipal College of Dental Sciences

Brief Summary: Although root canal treatment alleviates pain, postoperative pain afterroot canal treatment is a common problem (Gondim *et al.* 2010) and has been reported to range from 3% to 58% (Albashaireh*et al.*1998, Sathorn *et al.* 2008). The aetiology of postoperativepain following root canal treatment is multifactorial. It may be due toinadequate cleaning and shaping of the canal system, presence of periapicalpathosis, apical extrusion of debris, missed canals, over-instrumentation, and/orextrusion of irrigating solutions and intracanal medicaments (Seltzer 1986, Harrison*et al*. 1983, Siqueira *et al*. 2002). To prevent periapical tissue damage and reduce postoperativepain, a safe irrigation delivery system is desirable. Conventionalirrigation with a syringe and needle remains a widely accepted technique; however,it has been shown to be incapable of cleaning areas that are difficult toaccess such as the apical third of the canal and isthmus regions (Lee *et al.* 2004). Also, when needleirrigation is used an apical stagnation zone is created beyond the tip of theneedle where, irrigant exchange does not take place (Glulabivala *et al*. 2010) and as a result itseffectiveness is reduced. As a consequence, a number ofirrigation activation techniques, such as manual agitation, sonic or ultrasonicactivation and negative pressure systems, have been proposed to improve the movementof irrigants (agitation) within the canal and thus their efficacy within theroot canal system (Haapasalo *et al*.2010, Glulabivala *et al*. 2010, Mazo *et al*. 2012).It has been reported that irrigation devices have an effect on apicalextrusion of debris and irrigants (Mitchell *etal*. 2011, Boutsioukis *et al*. 2014)and have the potential to increase postoperative discomfort. This study evaluated postoperative pain after activation of the final irrigantsolution using XP Endo Finisher compared to traditional needle irrigationin teeth with symptomatic irreversible pulpitis and in teeth with necroticpulps and apical periodontitis.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 80

Inclusion Criteria

a)Healthy patients above 18 years of age; b)Molar teeth with symptomatic irreversible pulpitis or necrotic pulps; c)Patients with preoperative pain score that does not exceed 3 on a NRS-11 scale.

Exclusion Criteria

a)Patients who are not willing, or able to give informed consent; b)Patients who had taken analgesic or anti-inflammatory drugs within the last 12 hours; c)Non-restorable teeth; d)Teeth with calcified canals as seen radiographically; e)Patients allergic to non-steroidal anti-inflammatory (NSAIDs) drugs; f)Teeth with open/immature apex, and root resorption as seen radiographically; g)Teeth tender to percussion; h)Pregnant or lactating patients; i)Periodontally compromised teeth (loss of attachment).

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post treatment pain	6 h, 12 h, 24 h, 2nd day, 3rd day, 4th day, 5th day, 6th day and 7th day after shaping

Secondary Outcome Measures

Name	Time	Method
Analgesic intake after shaping	6 h, 12 h, 24 h, 2nd day, 3rd day, 4th day, 5th day, 6th day and 7th day after shaping

Trial Locations

Locations (1): Manipal College of Dental Sciences
🇮🇳
Udupi, KARNATAKA, India
Manipal College of Dental Sciences
🇮🇳Udupi, KARNATAKA, India
Vasudev Ballal
Principal investigator
09880626167
drballal@yahoo.com