JPRN-jRCTb040190118已完成未知
Therapeutic angiogenesis by cell transplantation with adipose-derived regenerative cells for critical limb ischemia - TACT-ADRC
Murohara Toyoaki0 个研究点目标入组 29 人开始时间: 2020年2月20日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 29
研究概览
简要总结
The results of this multicenter clinical trial demonstrate the safety, feasibility, and efficacy of transplanting autologous adipose tissue-derived mesenchymal stem cell progenitor cells for the purpose of antiangiogenic therapy.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 25age old 至 < 80age old（—）
- 性别
- All
入选标准
- •Target disease: PAD, TAO, and Collagen disease-associated vasculitis
- •Patients with
- •(1) 25<= Age <80
- •(2) CLI (Fontaine III-IV), who are not candidates for conventional therapies any more, including surgical revascularization
- •(3) informed consent
排除标准
- •Patients with
- •(1) Insufficient amount of adipose tissue
- •(2) No informed consent
- •(3) Expectation of life < 1 year
- •(4) A past 5 years or current history of malignant disease
- •(5) Untreated coronary heart disease or cerebrovascular diseases
- •(6) Untreated diabetic retinopathy
- •(7) Laboratory signs of chronic or acute inflammation
- •(8) Severe liver or kidney dysfunction
- •(9) Severe anemia or pancytopenia
- •(10) Pregnancy
- •(11) Others
研究者
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