Effects of Brisk Walking on Overweight/Obesity Population
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obesity
- Sponsor
- Guangdong Center for Disease Prevention and Control
- Enrollment
- 150
- Primary Endpoint
- BMI
- Last Updated
- 9 years ago
Overview
Brief Summary
1.Objective
The investigators aim to determine the effect of brisk walking prescription (> 10000 steps, > five days, per week) on body components and metabolic risk factors among patients with overweight/obesity. The objectives are as follow:
- The body components changes before/after the brisk walking prescription (> 10000 steps, > five days per week) intervention in overweight/obesity population;
- The metabolic risk factors changes before/after the brisk walking prescription (<10000 steps or <five days per week) intervention in overweight/obesity population
2.Study design This study is a prospective 4-month follow-up scheme in which patients were treated with the following intervention: > 10000 steps, > five days, per week. For individual follow-up, body components and metabolic risk factors will be tested before and after the study. Every participants will be followed up in community visits every month.
- Statistical analysis Statistical analysis will be performed using SPSS 16.0 version package (SPSS Inc., Chicago, IL.). Numerical data will be presented as mean ± standard deviation for normal distribution or otherwise median (interquartile range). Two-sided independent t-test is adopted for between-group comparison on end-points with normal distribution, otherwise non-parametric test. Row-Column table will be analyzed through chi-square test. P<0.05 is taken as statistical significant.
Detailed Description
Obesity/overweight has been recognized as one of the most important global health threats worldwide, which is closely related to metabolism syndrome including insulin resistance, hypertension, dyslipidemia and hyperglycemia. In 2013, an estimated 36.9% of men and 38.0% of women were overweight (BMI \>25 kg/m2) worldwide, with attributable fractions for CHD as high as 25% in the United States and 58% in the Asia-Pacific Region. Furthermore, a strong and continuous association between body mass index (BMI) and coronary heart disease (CHD) has been reported for values of BMI above 20kg/m2 . Numerous studies have recognized the role of physical activity in promoting moderate weight loss, weight loss maintenance, and having broad-reaching implications for cardiovascular disease mortality indices, as well as reducing healthcare expenditures. The findings of a recent review suggest that mild-to-moderate intensity exercises that include both aerobic and resistance training result in additional metabolic benefits in people with obesity or type 2 diabetes. Although weight loss is minimal, body composition improves. Brisk walking, at an individual level, prove to be the physical activity most easy to maintain and could be progressively increased in intensity, achieving a cardiorespiratory benefit and decrease adiposity in the unfit. Several small clinical trials reported inconsistent findings of short-term exercise programs on brisk walking among patients with overweight/obesity. However, these studies did not provide comparable indices, duration and intensity. Furthermore, the brisk walking effect of current physical activity guidelines on obesity/overweight is uncertain. The current study aimed to evaluate the effects of brisk walking ( \> 10000 steps, \> five days, per week) on body components and metabolic risk factors among patients with overweight/obesity.
Investigators
Xue-yan Zheng
Dr.
Guangdong Center for Disease Prevention and Control
Eligibility Criteria
Inclusion Criteria
- •The inclusion criterion is individual with sedentary behaviors, adding any of the following behavior:
- •individuals with BMI ≥24 kg/m2
- •waist circumstance ≥102cm in male; waist circumstance ≥88cm in female;
- •waist circumstance/hip circumstance\>1.0 in male; waist circumstance/hip circumstance\> 0.9 in female.
Exclusion Criteria
- •Participants were excluded with the presence of significant cardiac or pulmonary disease that could result in hypoxia or decreased perfusion.
Outcomes
Primary Outcomes
BMI
Time Frame: Change from Baseline BMI at 4 months
Body components
Secondary Outcomes
- Systolic blood pressure(Change from systolic blood pressure at 4 months)
- Diastolic blood pressure(Change from diastolic blood pressure at 4 months)
- Plasma glucose(Change from Plasma glucose at 4 months)
- visceral fat(Change from visceral fat at 4 months)
- abdominal circumstance(Change from abdominal circumstance at 4 months)
- body fat percentage(Change from body fat percentage at 4 months)
- visceral fat percentage(Change from visceral fat percentage at 4 months)
- waist circumstance/hip circumstance(Change from waist circumstance/hip circumstance at 4 months)
- serum triglycerides(Change from serum triglycerides at 4 months)
- serum total cholesterol(Change from serum total cholesterol at 4 months)
- high density lipoprotein-C(Change from high density lipoprotein-C at 4 months)
- low density lipoprotein-C(Change from low density lipoprotein-C at 4 months)
- heart rate(Change from heart rate at 4 months)