JPRN-jRCT2080225361招募中3 期
Randomized phase III study of S-1 based chemotherapy plus nivolumab versus S-1 based chemotherapy alone for patients with locally advanced/borderline resectable pancreatic cancer (Investigator initiated trial)
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- -
- 入组人数
- 216
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 ot applicable（—）
- 性别
- All
入选标准
- •1) Histologically or cytologically confirmed adenocarcinoma, adenocarcinoma squamous carcinoma of pancreatic cancer.
- •2) Patients who confirmed unresectable locally advanced or borderline resectable pancreatic cancer
- •3) The longest diameter of tumor does not exceed 10 cm by CT image
- •4) No sign of direct tumor invasion into gastrointestinal tract
- •5) Age 20 years old or older
- •6) Performance Status:0-1(ECOG)
- •7) No past history of surgery or chemotherapy for pancreatic cancer
- •8) No past history of radiation therapy to the abdomen
- •9) Sufficient organ functions
排除标准
- •1) Synchronous multiple cancers
- •2) Infectious disease to be treated
- •3) Past history of systemic steroid therapy (>10 mg/body of prednisolone) within 14 days
- •4) Active peptic ulcer
- •5) Interstitial pneumonia, pulmonary fibrosis, or inflammatory lung disease confirmed by medical history or imaging test
- •6) Pleural, pericardial, or abdominal effusion
研究者
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