PENETRATE
- Conditions
- pancreatic cancer
- Registration Number
- JPRN-jRCT2080225361
- Lead Sponsor
- -
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- recruiting
- Sex
- All
- Target Recruitment
- 216
1) Histologically or cytologically confirmed adenocarcinoma, adenocarcinoma squamous carcinoma of pancreatic cancer.
2) Patients who confirmed unresectable locally advanced or borderline resectable pancreatic cancer
3) The longest diameter of tumor does not exceed 10 cm by CT image
4) No sign of direct tumor invasion into gastrointestinal tract
5) Age 20 years old or older
6) Performance Status:0-1(ECOG)
7) No past history of surgery or chemotherapy for pancreatic cancer
8) No past history of radiation therapy to the abdomen
9) Sufficient organ functions
1) Synchronous multiple cancers
2) Infectious disease to be treated
3) Past history of systemic steroid therapy (>10 mg/body of prednisolone) within 14 days
4) Active peptic ulcer
5) Interstitial pneumonia, pulmonary fibrosis, or inflammatory lung disease confirmed by medical history or imaging test
6) Pleural, pericardial, or abdominal effusion
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method efficacy<br>Overall Survival
- Secondary Outcome Measures
Name Time Method efficacy<br>Progression Free Survival, Response rate etc<br>safety<br>Incidence of Adverse event, Incidence of Serious adverse event etc