Cellular Immunity, Cytomegalovirus Infection and Septic Shock in ICU Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 29
- 试验地点
- 2
- 主要终点
- Bring to light the quantitative and qualitative immunological modifications of the present cells NK before the arisen of an infection to CMV
研究概览
简要总结
This prospective study evaluate the immune status of patients admitted in ICU.CMV remains dormant in the body, but in people with immune deficiency, CMV could reactivate and cause life-threatening pneumonia.
详细描述
Candidates will be screened with medical history and blood tests.Then, 2 groups of 20 patients (with or without CMV reactivation) matched for CMV status will be compared for their immune system against CMV.
研究设计
- 研究类型
- Interventional
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age more than 18-year-old
- •Informed consent
排除标准
- •pregnant or lactating women,
- •adults under guardianship,
- •immunosuppression at the entrance to resuscitation,
研究组 & 干预措施
1
Infection to CMV
干预措施: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings (Other)
2
Group "control CMV"
干预措施: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings (Other)
结局指标
主要结局
Bring to light the quantitative and qualitative immunological modifications of the present cells NK before the arisen of an infection to CMV
时间窗: 24 months
次要结局
- Bring to light the quantitative and qualitative immunological modifications of cells NK in the consequences of an infectious shock(24 months)