NCT00699868
Completed
Not Applicable
Cellular Immunity, Cytomegalovirus Infection and Septic Shock in ICU Patients
Assistance Publique Hopitaux De Marseille1 site in 1 country29 target enrollmentStarted: March 2008Last updated:
ConditionsCytomegalovirus Infection
Overview
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 29
- Locations
- 1
- Primary Endpoint
- Bring to light the quantitative and qualitative immunological modifications of the present cells NK before the arisen of an infection to CMV
Overview
Brief Summary
This prospective study evaluate the immune status of patients admitted in ICU.CMV remains dormant in the body, but in people with immune deficiency, CMV could reactivate and cause life-threatening pneumonia.
Detailed Description
Candidates will be screened with medical history and blood tests.Then, 2 groups of 20 patients (with or without CMV reactivation) matched for CMV status will be compared for their immune system against CMV.
Study Design
- Study Type
- Interventional
- Intervention Model
- Parallel
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age more than 18-year-old
- •Informed consent
Exclusion Criteria
- •pregnant or lactating women,
- •adults under guardianship,
- •immunosuppression at the entrance to resuscitation,
Outcomes
Primary Outcomes
Bring to light the quantitative and qualitative immunological modifications of the present cells NK before the arisen of an infection to CMV
Time Frame: 24 months
Secondary Outcomes
- Bring to light the quantitative and qualitative immunological modifications of cells NK in the consequences of an infectious shock(24 months)
Investigators
Study Sites (1)
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