JPRN-UMIN000016550招募中2 期
ntreated IIIB/IV period with the EGFR mutation in the gene, phase II study of Gefitinib and the pemetrexed / bevacizumab combination maintenance therapy after Gefitinib and the cisplatin / pemetrexed / bevacizumab combination induction therapy for non-squamous epithelium non-small cell lung cancer of the latter recurrence - Untreated IIIB/IV period with the EGFR mutation in the gene, phase II study
International University of Health and Welfare Respiratory Disease Center0 个研究点目标入组 27 人开始时间: 2015年2月16日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 27
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) The case that a squamous cancer ingredient accounts for more than 50% in the case of mixed type with the squamous cancer. 2) A mixed case with small cell lung cancer. 3) We have EGFR resistance gene mutation (T790M). 4) With the symptom or metastases to brain case to need treatment such as a steroid or the antispasmodic. 5) The case with a history of the hemoptysis or the merger. 6) The case with a history, the merger of the following sputum bloody.d 7) A case that was given the radiotherapy for the chest. 8) It is a case of after the palliative irradiation for bone metastases or the metastases to brain except the primary tumor for less than two weeks. 9) The invasion of the primary tumor is found in in great vessels in trachea or lobar bronchus or the TNM classification T4 of the lung cancer handling agreement revision seventh edition partly. 10) A case with the superior vena caval syndrome. 11) A case with the interstitial pneumonia that is clear by chest CT or pulmonary fibrosis. 12) The case with a serious infection. 13) The case with serious complications. 14) The case with pleural effusion, ascitic fluid requiring treatment such as the drainage and the pericardial fluid. 15)A case with the multiple primary cancer of the activity. 16)A case with a history of serious drug allergy. 17)Uncontrollable hypertension < 160/100 18) A case with a history of less than one year before merger of cerebrovascular disorder with the symptom or registration. 19) Need to antiplatelet therapy or anticoagulation therapy without Aspirin 325 mg/day 20) Gastrointestinal perforation within 1 year 21) The case that it was judged mental disorder to become the clinical problem to have difficulty in registration to this study. 22) With pregnancy and the pregnant likelihood or women nursing or men in hope of fertility. 23)Inappropriate for this study judged by the attending physician
研究者
相似试验
已完成
2 期
Trimodality therapy in EGFR mutation status negative patients with stage IV non-small cell lung cancernon-small cell lung cancerJPRN-UMIN000006021Iseikai Hospital45
已完成
不适用
Prospective observational study of EGFR mutation allele frequency using Cell free DNAJPRN-UMIN000036149Hamamatsu University School of Medicine33
招募中
不适用
The continuous evaluation of EGFR mutation in EGFR-mutation positive lung cancer patients during EGFR TKI treatmentnon-small cell lung cancerJPRN-UMIN000037232Advanced Cancer Translational Research Institute100
已完成
不适用
a Study of EGFR & ALK Test in Lung cancer patients.CTRI/2017/10/010086Tata Memorial Hospital500
招募中
不适用
Clinical and Epidemiological Study of EGFR Mutation and EML4-ALK Fusion Gene Among Indian Patients with Adenocarcinoma LungCTRI/2012/04/002589Pfizer India500