JPRN-UMIN000013267招募中未知
A multi-institutional phase II study of preoperative chemotherapy with S-1, oxaliplatin and bevacizumab plus radiation for lower rectal cancer - A multi-institutional phase II study of preoperative chemotherapy with S-1, oxaliplatin and bevacizumab plus radiation for lower rectal cancer
Tokushima University Hospital Dept. of Digestive and Pediatric Surgery0 个研究点目标入组 45 人开始时间: 2014年3月10日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 80years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) Cases of obvious abnormality in the chest X-ray or interstitial pneumonia, pulmonary fibrosis with clinical symptoms or history of these disease 2) Patients with body cavity effusion requiring treatment 3) Patients with active double cancer, or curatively treated double cancer that have been no-treatment and disease-free interval for 5 years or less (However, skin cancer or carcinoma in situ is excluded) 4) Patients with primary lesions having severe stenosis that endoscope does not pass (However, cases of colostomy can be registered) 5) Cases with confirmed peritoneal metastasis on the image 6) Cases with infection, paralysis of the intestinal tract, intestinal obstruction 7) Cases with diarrhea (watery diarrhea). 8) Cases with uncontrolled diabetes 9) Cases with uncontrolled high blood pressure 10) Cases with complications (heart failure (cardiac dysfunction), liver failure, renal failure, etc.) that are judged to lead to serious trouble 11) Patients with history of thrombosis, cerebral infarction, myocardial infarction, pulmonary infarction and hemoptysis 12) Cases with intraperitoneal inflammation 13) Cases with perceived failure or severe paresthesia with dysfunction 14) Cases with symptomatic brain metastases 15) Cases with congenital bleeding diathesis orthe coagulation system abnormalities 16) Cases with inappropriate study entry due to psychosis or psychiatric symptoms 17) Cases with pregnant women, the intention or possibility of pregnant women and nursing mothers 18) Patients who had experienced severe allergic drug reactions 19) Cases corresponding to the contraindication to each drug of this study 20) Patients with a history of hypersensitivity to each drug 21) Patients receiving systemic administration(intravenous or oral) of continued steroids 22) Patients receiving anticoagulant 23) Any other cases who are regarded as inadequate for study enrollment by physicians
研究者
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