Uterine Artery Doppler and 11-14 / 20-22 Weeks of Gestation Pregnancy

Completed

• Conditions: Pregnancy Related
• Interventions: Other: uterine artery doppler measurement

• Registration Number: NCT04248660
• Lead Sponsor: Kanuni Sultan Suleyman Training and Research Hospital

Brief Summary

Uterine artery doppler measurements will be made at 11-14 weeks and 20-22 weeks of gestation, and the classification of these measurements according to type of delivery; and to investigate the change in the effect of delivery type on uterine artery flows on obstetric outcomes (maternal, fetal, neonatal outcomes).

Detailed Description

The first and second trimester perinatal examination results performed by the same operator from pregnant women who have applied to the clinic since the first trimester are removed from the ViewPoint 6.0 server and database and their uterine artery doppler values (uterine artery PI and RI values, presence of uterine artery notch), placental location, gestational week of measurement, blood pressures, PAPP-A and hCG MoM values, obstetric results (type of birth, week, weight, ante-postpartum complications), data to be generated from other hospital records will be saved to the base

Study Timeline

• Study Start: 2016-01-01
• Status Verified: 2020-01
• Primary Completion: 2020-01-01
• Study Completion: 2020-01-01
• Study First Submitted: 2020-01-28
• Study First Submitted QC: 2020-01-28
• Last Update Submitted: 2020-01-28
• Study First Posted: 2020-01-30
• Last Update Posted: 2020-01-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 750

Inclusion Criteria

• Gestational age 11-14. applying to the outpatient clinic at week
• Single spontaneous pregnancy
• Having a first pregnancy (primigravid nullipar) or having given birth once (primipar) (first birth by vaginal route or cesarean)
• Result of previous pregnancy with live birth (term delivery without obstetric complication)
• No intrauterine growth restriction in the first pregnancy
• Women who gave birth by cesarean section were not placed due to caesarean indication due to placental location-invasion anomaly, maternal chronic disease (hypertension, diabetes, coronary artery disease, etc.), placental detachment.

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Exclusion Criteria

• Multiple pregnancies
• Pregnancies with assisted reproductive techniques
• Placental anomaly in previous pregnancy
• Maternal chronic hypertension, preeclampsia, history of diabetes
• Pregnant women who smoke
• The presence of fetal chromosomal or structural anomaly
• two or more cesarean sections
• Having undergone non-cesarean surgery (myomectomy, septum or polyp resection ... etc)
• Presence of uterine structural anomaly

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Uterine artery doppler measurements	uterine artery doppler measurement	Uterine artery doppler measurements will be made in the same patients at 11-14 weeks and 20-22 weeks of pregnancy. Doppler results will be classified according to pregnancy results and primary results will be doppler findings.

Primary Outcome Measures

Name	Time	Method
Doppler results of 11-14 weeks of gestation in those who gave birth beforehand	10 months	uterine artery doppler values (uterine artery PI , presence of uterine artery notch)
Doppler results of 20-22 weeks of gestation in patients with previous cesarean section	10 months	uterine artery doppler values (uterine artery PI , presence of uterine artery notch)
Doppler results of 20-22 weeks of gestation in those who gave birth beforehand	10 months	uterine artery doppler values (uterine artery PI , presence of uterine artery notch)
Doppler results of 11-14 weeks of gestation in patients with previous cesarean section	10 months	uterine artery doppler values (uterine artery PI , presence of uterine artery notch)

Trial Locations

Locations (1)

Kanuni Sultan Süleyman Training and Research Hospital; 🇹🇷 Istanbul, Turkey