Comparison of Uterine Artery Doppler Measurements Performed at 11-14 and 20-22 Weeks of Gestation During Pregnancy According to Delivery Type and Number of Births and Investigation of the Effects on Obstetric Outcomes (Maternal, Fetal, Neonatal Results)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 750
- 试验地点
- 1
- 主要终点
- Doppler results of 11-14 weeks of gestation in those who gave birth beforehand
研究概览
简要总结
Uterine artery doppler measurements will be made at 11-14 weeks and 20-22 weeks of gestation, and the classification of these measurements according to type of delivery; and to investigate the change in the effect of delivery type on uterine artery flows on obstetric outcomes (maternal, fetal, neonatal outcomes).
详细描述
The first and second trimester perinatal examination results performed by the same operator from pregnant women who have applied to the clinic since the first trimester are removed from the ViewPoint 6.0 server and database and their uterine artery doppler values (uterine artery PI and RI values, presence of uterine artery notch), placental location, gestational week of measurement, blood pressures, PAPP-A and hCG MoM values, obstetric results (type of birth, week, weight, ante-postpartum complications), data to be generated from other hospital records will be saved to the base
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Gestational age 11-
- •applying to the outpatient clinic at week
- •Single spontaneous pregnancy
- •Having a first pregnancy (primigravid nullipar) or having given birth once (primipar) (first birth by vaginal route or cesarean)
- •Result of previous pregnancy with live birth (term delivery without obstetric complication)
- •No intrauterine growth restriction in the first pregnancy
- •Women who gave birth by cesarean section were not placed due to caesarean indication due to placental location-invasion anomaly, maternal chronic disease (hypertension, diabetes, coronary artery disease, etc.), placental detachment.
排除标准
- •Multiple pregnancies
- •Pregnancies with assisted reproductive techniques
- •Placental anomaly in previous pregnancy
- •Maternal chronic hypertension, preeclampsia, history of diabetes
- •Pregnant women who smoke
- •The presence of fetal chromosomal or structural anomaly
- •two or more cesarean sections
- •Having undergone non-cesarean surgery (myomectomy, septum or polyp resection ... etc)
- •Presence of uterine structural anomaly
结局指标
主要结局
Doppler results of 11-14 weeks of gestation in those who gave birth beforehand
时间窗: 10 months
uterine artery doppler values (uterine artery PI , presence of uterine artery notch)
Doppler results of 20-22 weeks of gestation in patients with previous cesarean section
时间窗: 10 months
uterine artery doppler values (uterine artery PI , presence of uterine artery notch)
Doppler results of 20-22 weeks of gestation in those who gave birth beforehand
时间窗: 10 months
uterine artery doppler values (uterine artery PI , presence of uterine artery notch)
Doppler results of 11-14 weeks of gestation in patients with previous cesarean section
时间窗: 10 months
uterine artery doppler values (uterine artery PI , presence of uterine artery notch)
次要结局
未报告次要终点
研究者
Pınar Kadirogulları
principal investigator, Pınar kadirogullari, M.D, Department of Obstetrics and Gynecology
Kanuni Sultan Suleyman Training and Research Hospital