Genicular nerve radiofrequency ablation with and without Duloxetine in chronic knee osteoarthritis
Not Applicable
- Conditions
- Health Condition 1: M179- Osteoarthritis of knee, unspecified
- Registration Number
- CTRI/2020/02/023270
- Lead Sponsor
- AIIMS Jodhpur Research Committee
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with diagnosis of radiologically verified grade III or IV
osteoarthritis according to the Kellgren-Lawrence Grading Scale who are not willing or not
fit for knee replacement due to concomitant comorbid medical diseases
Exclusion Criteria
Multiple joint involvement,
History of knee surgery
Experiencing acute knee pain with inflammation findings
Connective tissue disease affecting the knee joint
Serious psychiatric disorder or neurological disease
Sciatica
Current use of anticoagulant drugs
Having received intra-articular steroid or hyaluronic acid injection within the previous 3 months.
Patient not willing to participate in study
Allergy to duloxetine.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison in improvement of quality of Life by WOMAC score in both groups.Timepoint: 2 weeks, 1 month, 2 months and 3 months
- Secondary Outcome Measures
Name Time Method 1. Comparison of NRS score in both group <br/ ><br> 2. Total analgesic consumption in both groups <br/ ><br> 3. Patient satisfaction in both groups <br/ ><br> 4. To note the associated complications/ side effects of study drug- abnormal proprioception, numbness, paraesthesia, neuralgia, and motor weakness, nausea, constipation and loss of appetite. <br/ ><br>Timepoint: 2 weeks, 1 month, 2 months and 3 months