NCT00702429已完成不适用
Immunoregulation of Periodontal Disease
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Percentage of positive cells and intensity of expression for the molecules of surface studied there cytometric in stream
研究概览
简要总结
Our design is to test in hospital practice a selection of immune parameters that could assess the pathophysiology and progression of periodontal lesions.
详细描述
These parameters will be measured in 25 healthy volunteers and 25 moderate-to severe periodontal disese patients. Phagocytes will be tested phenotypically and functionally, both ex vivo and in vitro.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Persons appearing spontaneously at the consultation of parodontologie for parodontale disease,
- •persons agreeing to undergo a sampling of blood intended for the search
排除标准
- •Presence of a chronic or pointed pathology,
- •an age 18-year-old subordinate or 65-year-old superior,
- •pregnant women,
研究组 & 干预措施
1
Experimental
Patients achieve of parodontopathies
干预措施: Blood sampling (Other)
2
Placebo Comparator
Patients without parodontales diseases
干预措施: Blood sampling (Other)
结局指标
主要结局
Percentage of positive cells and intensity of expression for the molecules of surface studied there cytometric in stream
时间窗: 24 months
次要结局
- Rate of secretion of cytokines and the other substances(24 months)
- Detection and quantification of ARN messengers(24 months)
研究者
研究点 (2)
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