Immunoregulation of Periodontal Disease
Not Applicable
Completed
- Conditions
- Periodontal Disease
- Interventions
- Other: Blood sampling
- Registration Number
- NCT00702429
- Lead Sponsor
- Assistance Publique Hopitaux De Marseille
- Brief Summary
Our design is to test in hospital practice a selection of immune parameters that could assess the pathophysiology and progression of periodontal lesions.
- Detailed Description
These parameters will be measured in 25 healthy volunteers and 25 moderate-to severe periodontal disese patients. Phagocytes will be tested phenotypically and functionally, both ex vivo and in vitro.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 23
Inclusion Criteria
- Persons appearing spontaneously at the consultation of parodontologie for parodontale disease,
- persons agreeing to undergo a sampling of blood intended for the search
Exclusion Criteria
- Presence of a chronic or pointed pathology,
- an age 18-year-old subordinate or 65-year-old superior,
- pregnant women,
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 Blood sampling Patients achieve of parodontopathies 2 Blood sampling Patients without parodontales diseases
- Primary Outcome Measures
Name Time Method Percentage of positive cells and intensity of expression for the molecules of surface studied there cytometric in stream 24 months
- Secondary Outcome Measures
Name Time Method Rate of secretion of cytokines and the other substances 24 months Detection and quantification of ARN messengers 24 months
Trial Locations
- Locations (1)
Hopital de la Conception- Laboratoire d'Immunologie
🇫🇷Marseille, France