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Clinical Trials/NCT01418391
NCT01418391
Unknown
Not Applicable

the Effect of the Transversus Abdominis Plane (TAP) Block on the Minimal Laparotomy : a Randomized Controlled Trial

Kaohsiung Medical University Chung-Ho Memorial Hospital1 site in 1 country60 target enrollmentJune 2011
ConditionsColon Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colon Cancer
Sponsor
Kaohsiung Medical University Chung-Ho Memorial Hospital
Enrollment
60
Locations
1
Primary Endpoint
amount of post-operative morphine consumption
Last Updated
14 years ago

Overview

Brief Summary

Transversus abdominis plane block (TAP block) is a new regional block for abdominal wall.It had been reported the effect of post-operative pain control in minor abdominal surgery, such as inguinal hernia repair and appendectomy. On the other hand, because of the accurate of the pre-operative images, the minimal laparotomy for colon cancer was accomplished. Thus, the purpose of this study is to investigate the effect, such as analgesic effect, hemodynamic stability, and post-operative morphine consumption, of TAP block in minimal laparotomy.

Detailed Description

outcome measures: * Hemodynamic parameters (mean artery pressure, heart rate): recorded at time points of before induction of general anesthesia (baseline), after tracheal intubation immediately, after surgery started 1, 2, 3, 4, 5, 10, 15, 20, 25, and 30 min; then recorded them every 10 mins. * Post-operative morphine consumption: recorded morphine consumption at the time intervals of post-operative 0\~6 h, 6\~12 h, 12\~24 h, 24\~36 h, and 36\~48 h ,respectively. The total amount of morphine consumption was also counted.

Registry
clinicaltrials.gov
Start Date
June 2011
End Date
June 2012
Last Updated
14 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Anesthesiologists physical status I-III, ≧ 18 years of age, and needed double-lumen endotracheal tube (DLT) for thoracic surger

Exclusion Criteria

  • increased risk for regurgitation and pulmonary aspiration, history of gastroesophageal reflux, and pregnancy
  • a tracheostomy or prolonged ventilation on ICU was planned, patients were also excluded

Outcomes

Primary Outcomes

amount of post-operative morphine consumption

Time Frame: post-operative 48 hours

Secondary Outcomes

  • evaluation of post-operative pain status using visual analog scale (VAS) and superimposed face pain severity scale(post-operative 48 hours)

Study Sites (1)

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