Creatine Supplementation on Kidney Function in Resistance-trained Individuals

Not Applicable

Completed

• Conditions: Healthy Persons
• Interventions: Dietary Supplement: creatine; Dietary Supplement: placebo

• Registration Number: NCT01817673
• Lead Sponsor: University of Sao Paulo

Brief Summary

There is a claim that creatine supplementation might affect kidney function, especially in those consuming a high-protein diet. The aim of this study was to investigate the effects of creatine supplementation on kidney function in resistance-trained individuals ingesting a high-protein diet.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2011-07
• Primary Completion: 2013-02
• Study Completion: 2013-02
• Status Verified: 2013-03
• Study First Submitted: 2013-03-20
• Study First Submitted QC: 2013-03-22
• Last Update Submitted: 2013-03-22
• Study First Posted: 2013-03-25
• Last Update Posted: 2013-03-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 46

Inclusion Criteria

• participation in recreational resistance training
• consumption of a high-protein diet (≥ 1.2 g/Kg/d)

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Exclusion Criteria

• vegetarian diet
• use of creatine supplements in the past 6 months
• chronic kidney disease
• use of anabolic steroids.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
creatine	creatine	20 g/d for 5 d followed by 5 g/d throughout the trial
placebo (dextrose)	placebo	20 g/d for 5 d followed by 5 g/d throughout the trial

Primary Outcome Measures

Name	Time	Method
kidney function	3 months	as assessed by 51Cr-EDTA clearance

Secondary Outcome Measures

Name	Time	Method
proteinuria	3 months
albuminuria	3 months
serum urea	3 months
serum creatinine	3 months

Trial Locations

Locations (1)

Univsersity of Sao Paulo; 🇧🇷 Sao Paulo, Brazil