Study on the Antiaging Effect of Chinese Herb Drink
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- Total thiobarbituric acid reactive substances (TBARS)
研究概览
简要总结
The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.
详细描述
Background: Si-Wu-Tang (SWT) is a well-known traditional Chinese medicine (TCM) and widely used for treating various gynecological disorders. The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.
Methods: Sixty healthy voluntary subjects were recruited and assigned into two groups, who drank 125 mL of placebo (n=30) or SWT (n=30) for 6 continuous days per month during the following 6 months and vice versa with one month of washout period in between. During the initial, 3rd, 6th, 10th, and 13th months anthropometric measurements were performed as well as fasting blood samples were drawn for various biochemical assays. Abdominal ultrasonic and skin examination were performed at the initial, 6th and 13th months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy adults
排除标准
- •exclusion criteria were history of smoking, alcoholism
- •pregnant or lactating women,
- •chronic diseases, hepatic or renal dysfunction.
结局指标
主要结局
Total thiobarbituric acid reactive substances (TBARS)
时间窗: 6 months
次要结局
- Glutathione content (GSH)(6 months)
- GPx and glutathione reductase (GR) activity(6 months)
- Catalase(6 months)
- Total antioxidant capacity (TEAC)activities.(6 months)
- Glutamic pyruvic transaminase (GPT)(6 months)
- Superoxide dismutase (SOD) activity(6 months)
- Glutamic oxaloacetic transaminase (GOT)(6 months)
研究者
Chin Kun Wang
Professor
Chung Shan Medical University