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Clinical Trials/PACTR201706001651380
PACTR201706001651380
Recruiting
N/A

Physiological, psychological and behavioural effects of long-acting reversible contraception

South African Medical Research Council0 sites648 target enrollmentMay 25, 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Depression ,Sexual Dysfunction, menstrual disturbances
Sponsor
South African Medical Research Council
Enrollment
648
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 25, 2016
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional
Sex
Female

Investigators

Sponsor
South African Medical Research Council

Eligibility Criteria

Inclusion Criteria

  • be eligible for the study a woman must meet all of the following criteria:
  • ¿18\-35 years of age
  • ¿HIV\-seronegative
  • ¿Wants to use effective contraception
  • ¿Is able and willing to provide written informed consent
  • ¿Agrees to be randomised to either DMPA, NET\-En, or copper IUD
  • ¿Agrees to use assigned method for 18 months
  • ¿Agrees to follow all study requirements
  • ¿Intends to stay in the study area for the next 18 months, and willing and able to provide adequate locator information
  • ¿If recently pregnant, is at least 6 weeks post\-partum

Exclusion Criteria

  • ¿Reported medical contraindications (WHO MEC Category 3 or 4\) to copper IUDs, NET\-En, or DMPA, including:
  • orecent septic abortion
  • osuspicious unexplained vaginal bleeding
  • obreast, cervical, uterine, or ovarian cancer
  • ohigh BP or heart disease, venous thromboembolism, stroke, or diabetes
  • oliver disease or liver tumours
  • ouse of liver enzyme inducing medications (see appendix 9\)
  • ¿Is found to have pelvic tuberculosis or uterine fibroids with distortion of the uterine cavity on pelvic exam
  • ¿Has untreated mucopurulent cervicitis on exam, untreated pelvic inflammatory disease (PID), or untreated known gonorrhoea or chlamydia
  • ¿Has used DMPA, Net\-En, or an IUD in the last 6 months

Outcomes

Primary Outcomes

Not specified

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