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Web-Based Lifestyle Intervention for the Improvement of Health in African American Cancer Survivors

Not Applicable
Withdrawn
Conditions
Cancer Survivor
Interventions
Behavioral: Lifestyle Therapy
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
Registration Number
NCT04290962
Lead Sponsor
Roswell Park Cancer Institute
Brief Summary

This early phase I trial studies how well a web-based lifestyle intervention called Precision Nutrition Coaching Program works in improving health in African American cancer survivors. Participating in the web-based lifestyle intervention program reinforced with experienced lifestyle coaches and consisting of physical activity, nutritional/lifestyle habits, and educational lessons may help to improve overall health and well-being, fitness level, and quality of life in African American cancer survivors.

Detailed Description

PRIMARY OBJECTIVE:

I. To conduct a pilot implementation research study to determine the viability, safety, and effectiveness of the use of a 12-month, commercially available, web-based lifestyle behavioral medicine intervention program by individuals who are or have been a Witness Role Model (WRM) in the National Witness Project (NWP).

SECONDARY OBJECTIVE:

I. To examine the feasibility of this research to subsequently investigate the effects of optimal health and/or lifestyle related behavioral medicine interventions used to promote optimal health on mitigating cancer-related and overall mortality disparities in African Americans (AA), and comorbidity/ chronic disease(s) management over time. (EXPLORATORY)

OUTLINE:

Participants complete the 12-month Precision Nutrition Coaching Program web-based lifestyle intervention consisting of physical activity at home or a local gym, nutritional/lifestyle habit with a new focus biweekly, and educational lessons about health, nutrition, fitness, or behavior change.

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Has contacted study investigators using the contact information found on recruitment materials to convey their interest in participating
  • Verbally confirmed that they now currently or in the past have functioned as a WRM for NWP
  • Body mass index (BMI) >= 23
  • Weight stable over the past year (=< 10% change)
  • Current levels of physical activity were assessed and compared to United States (US) Centers for Disease Control and Prevention (CDC) Physical Activity (PA) guidelines (150 minutes of moderately intensive weekly physical activity)
  • Cleared to participate in an exercise program via the American College of Sports Medicine Exercise Pre-participation Health Screening Guidelines
  • Has access to internet and a computer/tablet etc
  • Has access to basic fitness equipment (dumbbells, resistance bands) and/or is willing to join a fitness facility
  • Is currently under the care of and has been assessed by a primary care physician within the last 12 months
  • Understands the investigational nature of this study and completes the process of informed consent per Institutional Review Board (IRB) approved protocol
Exclusion Criteria
  • Has uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
  • Is pregnant or nursing
  • Is unwilling or unable to participate
  • Has any condition which in the investigators' opinion(s) deems the subject an unsuitable candidate to participate in this study
  • Has metastatic cancer
  • Has an orthopedic disorder, neuromuscular disorder or other condition (e.g., arthritis, morbid obesity) that may significantly preclude participation in exercise or related behaviors
  • Is currently incarcerated (i.e., prisoner)

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Supportive Care (web-based lifestyle intervention)Quality-of-Life AssessmentParticipants complete the 12-month Precision Nutrition Coaching Program web-based lifestyle intervention consisting of physical activity at home or a local gym, nutritional/lifestyle habit with a new focus biweekly, and educational lessons about health, nutrition, fitness, or behavior change.
Supportive Care (web-based lifestyle intervention)Lifestyle TherapyParticipants complete the 12-month Precision Nutrition Coaching Program web-based lifestyle intervention consisting of physical activity at home or a local gym, nutritional/lifestyle habit with a new focus biweekly, and educational lessons about health, nutrition, fitness, or behavior change.
Supportive Care (web-based lifestyle intervention)Questionnaire AdministrationParticipants complete the 12-month Precision Nutrition Coaching Program web-based lifestyle intervention consisting of physical activity at home or a local gym, nutritional/lifestyle habit with a new focus biweekly, and educational lessons about health, nutrition, fitness, or behavior change.
Primary Outcome Measures
NameTimeMethod
Rate of enrollmentUp to 12 months
Program effectivenessUp to 12 months

The effects of the lifestyle intervention program will be ascertained via primarily subjective, self-reported assessments administered at pre-intervention, post-intervention, and a follow-up. Subjective data will be validated through the collection of objective data in a subset of local participants via in-person assessments. Generalized linear mixed model methods, specifically a repeated measures analysis of variance with a random participant effect, as well as fixed effects for time and interaction will be used.

Rate of refusalUp to 12 months
Incidence of physical activity related injuriesUp to 12 months

Biweekly inquiries about possible injuries will be conducted.

Program retentionUp to 12 months

Will be measured by the proportion of participants who are still participating in the study at the end of the 12-month intervention.

Program adherence rateUp to 12 months

Measured by participation and online tracking of activity completion (workout, habit, and lessons). An overall adherence score will be calculated by averaging the percentage of time each of the 3 activities were completed by each participant over the 12-month intervention.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

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