Comparing Formulations of Mechanical Power Using Geometric Methods

Completed

• Conditions: Ventilator-Induced Lung Injury; Acute Respiratory Distress Syndrome
• Interventions: Procedure: Mechanical ventilator adjustment for PCV; Procedure: Mechanical ventilator adjustment for VCV

• Registration Number: NCT06413472
• Lead Sponsor: Başakşehir Çam & Sakura City Hospital

Brief Summary

We aimed to compare mechanical power and energy values using geometric methods at varying inspiratory rise times.

Detailed Description

In this study, the researchers aim to compare the mechanical power and energy values calculated using the geometric method in Volume-Controlled Ventilation (VCV) and Pressure-Controlled Ventilation (PCV) modes at different inspiratory rise times.

Study Timeline

• Study Start: 2024-01-01
• Study First Submitted: 2024-05-09
• Study First Submitted QC: 2024-05-13
• Study First Posted: 2024-05-14
• Primary Completion: 2024-12-01
• Study Completion: 2024-12-15
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-12
• Last Update Posted: 2025-02-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• ARDS (Acute Respiratory Distress Syndrome) patients.
• Patients who are deeply sedated.
• Patients ventilated in:
• Pressure-Controlled Ventilation (PCV or PRVC) mode, or
• Volume-Controlled Ventilation (VCV) mode.
• Patients within the 24-48 hour period of their stay in the intensive care unit.

Exclusion Criteria

• Patients with incomplete data.
• Patients diagnosed with:
• COPD (Chronic Obstructive Pulmonary Disease),
• Heart failure.
• Pregnant patients.
• Patients with a thoracopleural fistula.
• Hemodynamically unstable patients.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
ARDS patients-PCV	Mechanical ventilator adjustment for PCV	Intubated patients with a diagnosis of ARDS in the intensive care unit, ventilated using Pressure-Controlled Ventilation (PCV).
ARDS patients-VCV	Mechanical ventilator adjustment for VCV	Intubated patients with a diagnosis of ARDS in the intensive care unit, ventilated using Volume-Controlled Ventilation (VCV).

Primary Outcome Measures

Name	Time	Method
MPgeo	40 minute	The mechanical power (MPgeo) values measured using the geometric method .
Energy	40 minute	Energy values measured using the geometric method .

Trial Locations

Locations (1)

Basaksehir Cam Sakura City Hospital; 🇹🇷 Istanbul, Turkey