The relationship between contrast media volume and tube voltage in computed tomography of the liver, for optimal enhancement based on total body weight: A randomized controlled trial. [COMpLEx trial]
Completed
- Conditions
- liver lesionsneoplasm100179901001981510027655
- Registration Number
- NL-OMON46148
- Lead Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 256
Inclusion Criteria
Patients referred for abdominal CT
Patients older than 18 years and competent to sign an informed consent
Exclusion Criteria
Hemodynamic instability
Pregnancy
Renal insufficiency (defined as Glomerular Filtration Rate (GFR) < 30 mL/min
Iodine allergy
Age <18 years
Absence of informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To evaluate the possibilities to reduce radiation dose and CM volume in<br /><br>patients receiving an abdominal CT scan. All scans performed in portal venous<br /><br>phase and with or without an unenhanced and/or arterial and/or delayed scan are<br /><br>included. A scan is defined diagnostic as an attenuation increase of >= 50 HU<br /><br>between the unenhanced and the portal venous phase scan is achieved. We<br /><br>hypothesise that in abdominal CT the tube voltage and therefore CM volume can<br /><br>be reduced with a sufficient liver enhancement of >= 50 HU.</p><br>
- Secondary Outcome Measures
Name Time Method