A randomized, placebo-controlled, partially blinded (drug versus placebo) trial of early corticosteroid therapy in Vietnamese children and young adults with suspected dengue infection

niversity of Oxford (UK)0 个研究点目标入组 225 人开始时间: 2008年10月21日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Aged between 6 and 20 years, either sex
•2. Weight at least 20 kg
•3. Clinical suspicion of dengue, with a positive rapid test for dengue non-structural protein 1
•4. Fever for less than or equal to 72 hours
•5. Informed consent

•1. Signs or symptoms suggestive of any other acute infectious disease
•2. Any evidence of significant complications of dengue, e.g., mucosal bleeding, jaundice, neurological compromise, shock, inability to tolerate oral medication
•3. Any prior history of serious physical illness, or any chronic condition requiring regular follow up
•4. Any history of psychiatric disorder or behaviour disturbance
•5. Current or recent (within 3 months) use of any medication other than drugs for symptomatic relief (analgesics, decongestants, etc.)
•6. Any history of an adverse drug reaction to any medication
•7. Pregnancy (enrolment within one month of last menstrual period [LMP] in post-pubertal females)

发起方

niversity of Oxford (UK)