Combined therapy with low dose aspirin and calcium supplements during second trimester to reduce the risk of superimposed preeclampsia in pregnant women with chronic hypertension: a randomized-controlled trial

Phase 4

• Conditions: pregnancy with chronic hypertension; chronic hypertension in pregnancy, aspirin, calcium, preeclampsia

• Registration Number: TCTR20170629006
• Lead Sponsor: ONE

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-29
• Study Completion: 2018-05-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: Female
• Target Recruitment: 104

Inclusion Criteria

1.Pregnant woman with chronic hypertension > 20 years
2.ANC and planning to delivery at Khon Kaen Hospital and Srinagarind Hospital
3.Carrying a live, structurally normal, singleton fetus between 13 to16 weeks of gestation
4.Participants already informed consent

Exclusion Criteria

1.History of bleeding disorders
2.Thrombocytopenia; platelet count < 140,000/mm3
3.Placenta previa
4.Asthma
5.Allergy to aspirin
6.Planning to delivery in other hospitals

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
event of preeclampsia 31 May 2018 data collection form

Secondary Outcome Measures

Name	Time	Method
neonatal outcome 31 May 2018 data collection form