Stem Cell Augmented, Elutriated Grafts for Allogeneic Bone Marrow Transplantation

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins2 个研究点分布在 1 个国家开始时间: 1997年3月最近更新: 2014年5月2日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
试验地点: 2

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy used to kill tumor cells. Sometimes the transplanted cells can make an immune response against the body's normal tissues. Stem cells that have been treated in the laboratory to remove lymphocytes may prevent this from happening.

PURPOSE: Clinical trial to prevent graft-versus-host disease in patients undergoing bone marrow transplantation.

详细描述

OBJECTIVES:

Determine whether stem cell augmented, elutriated grafts prevent graft versus host disease in patients undergoing allogeneic bone marrow transplantation.

OUTLINE: Patients receive elutriated CD34+ augmented donor bone marrow on day 0.

Bone marrow samples are obtained before day 100, around 6 months, and 1 year after transplant.

PROJECTED ACCRUAL: Not specified

研究设计

研究类型: Interventional
主要目的: Supportive Care

入排标准

年龄范围: — 至 65 Years（Child, Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

未提供

排除标准

未提供

研究者

发起方

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

申办方类型

Other

研究点 (2)

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