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Clinical Trials/CTRI/2021/06/034115
CTRI/2021/06/034115
Not yet recruiting
Phase 1

Single Institutional Pilot Study Of Low Dose Whole Lung Radiation Therapy In Moderate To Severe COVID-19 Pneumonia Patients.

ot yet applied0 sites0 target enrollmentTBD
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Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Not specified
Sponsor
ot yet applied
Status
Not yet recruiting
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
ot yet applied

Eligibility Criteria

Inclusion Criteria

  • •1\. Patient with informed consent
  • •2\. Age \>18 yrs and \<90 yrs
  • •3\. COVID\-19 RT\-PCR positive
  • •4\. RT\-PCR done less than 7days
  • •5\. Moderate to severe case (NEWS 2 score\- more than or equal to 5\)
  • •6\. SPO2\- \<90%, RR\- \>24 per minute in Room air
  • •7\. KPS \>60
  • •8\. HRCT suggestive of Interstitial pneumonia with CORADS 4\-6 and CT severity score of moderate to severe.
  • •9\. Patient able to lie supine for Radiation therapy

Exclusion Criteria

  • •1\. Patient on mechanical ventilator support
  • •2\. Hemodynamically unstable patient
  • •3\. Pregnancy and lactating mothers
  • •4\. Known prior systemic use of the following drugs: Bleomycin, Carmustine, Methotrexate, Busulfan,Cyclophosphamide, or Amiodarone
  • •5\. History of lung lobectomy or pneumonectomy.
  • •6\. History of receiving immunotherapy within the past 6 months.
  • •7\. History of Chronic obstructive pulmonary disease, Severe Left Ventricular Dysfunction and patients on beta blockers.

Outcomes

Primary Outcomes

Not specified

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