ow Dose Whole Lung Radiation Therapy for COVID-19 Pneumonia

Phase 1

• Conditions: Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

• Registration Number: CTRI/2021/06/034115
• Lead Sponsor: ot yet applied

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patient with informed consent

2. Age >18 yrs and <90 yrs

3. COVID-19 RT-PCR positive

4. RT-PCR done less than 7days

5. Moderate to severe case (NEWS 2 score- more than or equal to 5)

6. SPO2- <90%, RR- >24 per minute in Room air

7. KPS >60

8. HRCT suggestive of Interstitial pneumonia with CORADS 4-6 and CT severity score of moderate to severe.

9. Patient able to lie supine for Radiation therapy

Exclusion Criteria

1. Patient on mechanical ventilator support

2. Hemodynamically unstable patient

3. Pregnancy and lactating mothers

4. Known prior systemic use of the following drugs: Bleomycin, Carmustine, Methotrexate, Busulfan,Cyclophosphamide, or Amiodarone

5. History of lung lobectomy or pneumonectomy.

6. History of receiving immunotherapy within the past 6 months.

7. History of Chronic obstructive pulmonary disease, Severe Left Ventricular Dysfunction and patients on beta blockers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified