Evaluation of treatment of constipation induced infectio
Phase 3
Recruiting
- Conditions
- ConstipationConstipation.K59.0
- Registration Number
- IRCT20201226049834N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Grade IIb, III upper-lower limb burns
Burn percentage between 20 to 30
Exclusion Criteria
History of neurological diseases including dementia, Alzheimer's, Parkinson's
History of psychologic illnesses including known and treated depression and anxiety, mania and schizophrenia
Any allergies to laxatives or enzymes used
History of Inflammatory bowel disease and Irritable bowel syndrome
Coma or loss of consciousness
Moderate to severe water and electrolyte disturbance
Simultaneous presence of other traumas other than burns
Perineal or anal burns
History of diabetes, hypertension, heart, respiratory, liver and kidney
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of patients' constipation status. Timepoint: Maximum three days and examination every 12 hours from the beginning of the interventions. Method of measurement: Examination and clinical questions.;Wound infection caused by constipation. Timepoint: Duration of hospitalization of patients in infectious wards and intensive care. Method of measurement: Clinical examination and laboratory results.
- Secondary Outcome Measures
Name Time Method Incidence of burn wound infection. Timepoint: Duration of hospitalization of patients in infectious wards and intensive care. Method of measurement: Clinical examination and laboratory results.;Incidence of constipation. Timepoint: Duration of hospitalization of patients in infectious wards and intensive care. Method of measurement: Patient records and clinical examinations.