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A Study to evaluate the Efficacy and Tolerability of ActiTape in Patients with Pain in Knee Joint due to Mild to Moderate Osteoarthritis

Phase 2
Conditions
Health Condition 1: null- Mild to Moderate Knee Osteoarthritis
Registration Number
CTRI/2013/02/003402
Lead Sponsor
utriworks Limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
14
Inclusion Criteria

1.Ambulatory adult patients of either sex aged 30-65 years.

2.Patients with moderate OA of the knee, which can be clinically, categorized as ARA functional Class II and III and with radiological confirmation of Kellgren Lawrence Grade II and III.

3.Patientâ??s functional assessment of overall pain score should be >= 50 mm on a 100 mm VAS for pain at baseline visit.

4.Patients receiving a stable dose of oral calcium or chondrogenic supplements for at least past 1 month and/or a stable dose of NSAIDs for the past 1 week will be eligible for inclusion

Exclusion Criteria

1.Patients of any form of arthritis other than osteoarthritis.

2.Arthroscopy of either knee in the past year.

3.Administration of intra-articular or oral steroids in the past 3 month or intra articular hyaluronic acid in the last 9 months or parenteral use of NSAIDs.

4.Patients requiring immediate surgery for knee.

5.Pregnant / lactating women and women who are planning to get pregnant

6.Recent ( 3 months) participation in a clinical study

7.History of major chronic hepatic, cardiovascular, neurological or immunosuppressive conditions or the presence of any infections

8.Patients with a risk of Deep Vein Thrombosis (DVT) as depicted by a score of >=3 on the Wellâ??s questionnaire

9.Patients with localized trauma to the lower limb

10.Dermatological conditions affecting the lower limb

11.History of skin irritation on application of bandages/tapes

12.A psychiatric condition, chronic alcohol or drug abuse problem as evidenced by withdrawal symptoms

13.Patients otherwise judged by the investigator to be inappropriate for inclusion in the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1.Pain - Visual analogue scale (VAS) <br/ ><br>2.Time up-and-go test, <br/ ><br>Patientsâ?? and Investigator global assessment <br/ ><br>3.Unilateral anterior reach test. <br/ ><br> 4.Medial step-down testTimepoint: At Day 0,Day 3,Day 6,Visit 5,Day 8,Day 11 and Day 14 <br/ ><br> <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
noneTimepoint: none
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