ACTRN12615001009505招募中4 期
In patients having dental extractions, is continuing new oral anticoagulants (NOACs) as safe as continuing warfarin in terms of bleeding amount?
Dr Jennifer Curnow0 个研究点目标入组 400 人开始时间: 2015年9月28日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 400
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit(—)
- 性别
- All
入选标准
- •1. Requires simple or surgical dental extraction(s).
- •2. On therapeutic dose of dabigatran, rivaroxaban, apixaban or warfarin.
- •3. Able to give informed consent.
- •4. Age 18 or above.
排除标准
- •1. Women who are pregnant.
- •2. Concomitant use of dual anti-platelet therapy.
- •3. Inherited disorder of haemostasis.
- •4. Platelet count < 50 x 10^9/L.
- •5. Procedure for which operator requires OAC interruption.
- •6. OAC already ceased prior to procedure.
- •7. Patient on warfarin and INR < 2 or > 4.
- •8. Severe active oral infection associated with facial swelling.
- •9. Cockroft-Gaultcreatinine clearance < 25 ml/min for patients on dabigatran, < 30 ml/min for patients on rivaroxaban or apixaban.
- •11. Surgical extraction of wisdom teeth.
研究者
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