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Clinical Trials/NCT05848414
NCT05848414
Completed
Not Applicable

Short Term Outcomes in Hospitalized Patients With Liver Cirrhosis

Assiut University1 site in 1 country100 target enrollmentFebruary 7, 2024
ConditionsLiver Cirrhosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Liver Cirrhosis
Sponsor
Assiut University
Enrollment
100
Locations
1
Primary Endpoint
evaluate the 90-day mortality of patients admitted with liver cirrhosis
Status
Completed
Last Updated
7 months ago

Overview

Brief Summary

This study will be conducted to assess the baseline characteristics and evaluate the 90-day mortality of patients admitted with liver cirrhosis. Also, the study will be done to identify the risk factors of 90-day mortality.

Detailed Description

Liver cirrhosis is the end spectrum of all chronic liver diseases characterized by advanced fibrosis, scarring, and formation of regenerative nodules leading to hepatic architectural distortion. Liver cirrhosis is a major cause of health burden worldwide. According to the Global Burden of Disease study, liver cirrhosis caused 1.2% of global disability-adjusted life years and 2% of all deaths worldwide in 2010, the 14th leading cause of mortality. The progress rate of compensated cirrhosis to decompensated cirrhosis is approximately 58% and once it progresses to decompensated cirrhosis, its mortality rate within 5 years becomes 85% without liver transplantation. Since the progression of cirrhosis is accelerated each time a complication recurs, the management and treatment of the complication are critical in enhancing the quality of life and the life expectancy of patients . Post-discharge outcomes are an integral component of healthcare, as they may aid in determining the success and longevity of treatment and how clinicians approach future cases . This study will focus on the short-term outcomes of patients hospitalized with liver cirrhosis to provide insight into methods for future healthcare interventions.

Registry
clinicaltrials.gov
Start Date
February 7, 2024
End Date
July 7, 2025
Last Updated
7 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Esraa Hassan Mohamed kotbey

Doctor

Assiut University

Eligibility Criteria

Inclusion Criteria

  • \- diagnosis of liver cirrhosis, adult (age ≥ 18 years old) and patients willing to give consent during the selected period.

Exclusion Criteria

  • \- Patients with ages \< 18 years or patients that will be lost on follow-up will be excluded from the study.

Outcomes

Primary Outcomes

evaluate the 90-day mortality of patients admitted with liver cirrhosis

Time Frame: 90 days

Mortality

Secondary Outcomes

  • identify the risk factors of 90-day mortalit(90 days)

Study Sites (1)

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