Effect of Open-placebo Intervention on Cycling Performance

Not Applicable

Completed

• Conditions: Exercise Performance
• Interventions: Behavioral: Control; Behavioral: Open-placebo

• Registration Number: NCT03977246
• Lead Sponsor: University of Sao Paulo

Brief Summary

This study evaluates the effect of an open-label placebo intervention on cycling time-trial performance.

Detailed Description

This study investigated the effect of open-placebo on cycling time-trial (TT) performance. Twenty-eight trained female cyclists completed a 1-km cycling TT following a control session or an open-placebo intervention. The intervention consisted of an individual presentation, provided by a medic, in which the concept of open-placebo was explained to the participant, before she ingested two red and white capsules containing flour; 15 min later, they performed the TT. In the control session, the participant sat quietly for 20 min.

Study Timeline

• Study Start: 2018-05-01
• Primary Completion: 2018-08-30
• Study Completion: 2018-09-30
• Status Verified: 2019-06
• Study First Submitted: 2019-06-04
• Study First Submitted QC: 2019-06-04
• Last Update Submitted: 2019-06-05
• Study First Posted: 2019-06-06
• Last Update Posted: 2019-06-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• Females aged between 18 and 45 years old;
• A minimum of one-year training experience in cycling.

Exclusion Criteria

• Smokers
• Chronic disease
• Prior or current use of steroids
• Use of creatine in the last 6 months
• Use of beta-alanine in the last 6 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Control	Control	The control session
Open-placebo	Open-placebo	The open-placebo intervention session

Primary Outcome Measures

Name	Time	Method
Exercise performance	20-min following open-placebo intervention	Change in 1 km cycling time-trial performance

Secondary Outcome Measures

Name	Time	Method
Blood lactate	Immediately post-exercise	Change in blood lactate concentration

Trial Locations

Locations (2)

School of Physical Education and Sport - USP; 🇧🇷 Sao Paulo, Brazil

University of Sao Paulo; 🇧🇷 Sao Paulo, Brazil