The effect of Zishen Yutai pills on the improvement of IVF oocyte utilization rate in POI patients: a prospective multicenter randomized controlled trial

Phase 4

Recruiting

• Conditions: premature ovarian insufficiency

• Registration Number: ITMCTR2000003200
• Lead Sponsor: Reproductive Medical Center of Ruijin Hospital School of Medicine, Shanghai Jiaotong University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-02-20

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

1. Volunteer to participate in this study, be willing to use medication according to the treatment plan and follow up, and sign the informed consent;
2. The patient was in good health, and there were no obvious abnormalities in clinical physical examination and laboratory examination (except for POI related indicators);
3. Aged between 20 and 40 years; Conforming to the preliminary screening conditions of POI (Poseidon Group 3 and Group 4) as ovarian basal sinus follicles less than 5; AMH <1.2ng/ml;
4. Hysteroscopy or fallopian tube examination: the uterine cavity shape is normal; normal uterine cavity shape after the operation drugs and the like;
5. The karyotype of the couple is normal and there is no genetic disease.

Exclusion Criteria

1. Patients with severe diseases of the respiratory system or endocrine system or nervous system or cardiovascular system or diseases of the digestive system or genitourinary system or family history of hereditary diseases;
2. Who has suffered from or is suffering from contraindications of Zishen Yutai pills or alleric to Zishen Yutai pills;
3. Smoking more than 20 cigarettes a day;
4. Patients with genital tract virus infection and cervical laxity; With reproductive organ malformation or chromosome abnormality;
5. Patients with HBV, HCV, HIV or severe autoimmune diseases or tumors or cancers;
6. Patients with endometrial lesions.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified