The Effect of Astaxanthin Administration on poor Ovarian Response

Phase 3

• Conditions: Poor ovarian response.; Other ovarian dysfunction: Poor ovarian response; E28.8

• Registration Number: IRCT20230223057510N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 26 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

POR will be diagnosed based on PSEIDON: (i) age > 35 years,
(ii) anti-Mullerian hormone (AMH) < 1.2 ng/mL or antral follicle count (AFC) < 5
The couple should be a candidate for ICSI

Exclusion Criteria

including spontaneous pregnancy,
history of ovarian surgery,
autoimmune or endocrine disease (diabetes, thyroid dysfunction, presence of anti-thyroid antibody or polycystic ovary),
hyperprolactinemia,
severe endometriosis (stages III and IV based on AFS-rAFS classification of endometriosis),
recurrent Spontaneous miscarriage,
ovarian tumor,
chromosomal defect,
uterine disorder,
more than 3 previous IVF cycles,
severe male factor infertility (especially non-obstructive azoospermia),
history of taking drugs that affect ovarian function such as steroids and OCP.
Also, people who have used antioxidant supplements, vitamins or drugs affecting the hormonal profile 3 months before the start of the plan will not be included in the plan.
have any history of male factor infertility.

Study & Design

• Study Type: interventional
• Study Design: Not specified