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临床试验/CTRI/2025/07/090552
CTRI/2025/07/090552尚未招募不适用

Use of Yastimadhu Panchavalkal Ghrut suppository in relieving symptoms of Parikartika (Fissure in Ano) in conservative management of Fissure in Ano

DMM Ayurved Mahavidyalaya Yavatmal1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年7月19日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
Parameters will be noted down before and after treatment

研究概览

简要总结

Parikartika (Fissure in Ano) is most common among anorectal diseases.

According to Ayurveda when a person of Kshinbala, Mrudukoshta, Mandagni or Ruksha prakruti takes

Ati-tikshna, Ati-ushna, Ati-lawan or Ati-ruksha medicine, his Pitta and Vata gets  polluted due to which a phenomenon called ’Parikartika’ occurs.

Parikartika is associated with symptoms like burning pain, bleeding, ulcer and sometimes pruritis.

Yastimadhu Panchavalkal Ghrut suppository contains Yastimadhu and Panchavalkal.

Yastimadhu is Madhura rasa pradhan Sheeta virya and act as a Pitta,Rakta and Vata shamaka. It helps in vranaropana, vednashamana, shotha shamana. Yastimadhu’s active compounds reduce inflammation in the anal region, alleviating pain and promoting healing.

In Panchavalkal

  1. Vat helps in dahashaman, wound healing and having anti-inflammatory properties.

  2. Udumbar helps in wound healing.

  3. Ashvathha helps in raktavikar and dahshaman.

  4. Plskha heps in raktaj vikar.

  5. Vetas works as vranashodhka.

So, I am using Yastimadhu Panchavalkal Ghrut suppository in relieving symptoms of Parikrtika [Fissure in Ano] in conservative management of Fissure in Ano.

Follow up will be taken on 1st,2nd,3rd,4th,5th,6th,7th,9th,11th,13th, 15th,18th, 21st, and 28th day.

研究设计

研究类型
Interventional
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients suffering from Fissure in Ano (acute or chronic) in which surgery is not indicated.
  • 2.Patients irrespective of caste, religion, sex, economic status.
  • Patients who can give written consent and regular follow up.
  • 4.Patients between age group 18 to 60 years.
  • 5.Patients suffered from Parikartika with controlled Diabetes mellitus and controlled Hypertension.

排除标准

  • 1.Fissure in Ano associated with inflamed sentinel tag, fistula in Ano, hemorrhoids, anorectal abscess, ulcerative colitis, Crohns disease, CA rectum, rectum prolapse and rectal polyp.
  • 2.HIV, HBsAg positive patient.
  • 3.Sexually transmitted diseases.
  • Lactating and breastfeeding womens.

结局指标

主要结局

Parameters will be noted down before and after treatment

时间窗: 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 9th, 11th, 13th, 15th, 18th, 21st, 28th day

Patients will be diagnosed based on symptoms of Parikartika (Fissure in Ano) explained in Ayurvedic and Modern texts

时间窗: 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 9th, 11th, 13th, 15th, 18th, 21st, 28th day

1 Pain

时间窗: 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 9th, 11th, 13th, 15th, 18th, 21st, 28th day

2 Bleeding

时间窗: 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 9th, 11th, 13th, 15th, 18th, 21st, 28th day

3 Ulcer

时间窗: 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 9th, 11th, 13th, 15th, 18th, 21st, 28th day

4 Itching

时间窗: 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 9th, 11th, 13th, 15th, 18th, 21st, 28th day

次要结局

  • 1)Cured –70-100% relief in signs & symptoms.(2) Markedly improved-50-70% relief in signs & symptoms.)

研究者

发起方
DMM Ayurved Mahavidyalaya Yavatmal
申办方类型
Other [Government Aided College ]
责任方
Principal Investigator
主要研究者

Dr Pandurang Eknathrao Dhage

DMM Ayurved Mahavidyalaya Yavatmal

研究点 (1)

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